Host Response to Urinary Tract Infection in Women
This study is being done to identify those elements of the immune response that may predispose a woman to recurrent urinary tract infection. We suspect that lesser effectiveness of certain components of the host response will lead to recurrent urinary tract infection. We will also evaluate the role that the bladder reservoir may play in recurrent urinary tract infection.
Urinary Tract Infection
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Host Response to Urinary Tract Infection in Women|
- Determine elements of the immune response that may predispose a woman to recurrent urinary tract infection [ Time Frame: 2017 ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
whole blood,serum, urine
|Study Start Date:||February 2008|
|Study Completion Date:||July 2012|
|Primary Completion Date:||July 2012 (Final data collection date for primary outcome measure)|
Women with current symptoms of a urinary tract infection
Procedures subjects will undergo once they have read and signed the consent are:
Questions about their medical and sexual history and current symptoms of urinary tract infection. They will be asked to provide a clean catch urine sample. We will collect periurethral, vaginal and rectal swabs. Blood will collected. They will be given a diary to take home and record all episodes of sexual intercourse, contraceptive use, vaginal and urinary symptoms and medication use.
They will be given standard treatment for the current urinary tract infection. Follow-up visits will be scheduled 2 weeks,one month,two month and three month after initial visit.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00642070
|United States, Washington|
|University of Washington/Hall Health Primary Care Center|
|Seattle, Washington, United States, 98195|
|Principal Investigator:||Ann E Stapleton, M.D.||University of Washington|