Primary Outcome Measures:
- The patients connecting or disconnecting to the ventilators affected the RSBI values but not their predictive accuracies. [ Time Frame: Before the patient processing weaning trials ] [ Designated as safety issue: No ]
Secondary Outcome Measures:
- Changes in FiO2 and CPAP settings have no effect on RSBI values but ventilator methods with FiO2 21% have higher incidence of adverse reactions. [ Time Frame: Before the patient processing weaning trials ] [ Designated as safety issue: No ]
98 ready for weaning patients were included and divided into success (n=71) and failure (n=27) groups based upon their weaning outcome. Before weaning, the RSBI values were determined under the patients disconnecting from the ventilator (RA-no ventilator) and still connecting to the ventilator with 4 different settings (fraction of inspired oxygen (FiO2) 21 or 40% combined with continuous positive airway pressure (CPAP) 0 or 5 cm H2O). The patients were extubated after completing the weaning trials. Successful weaning was defined as patients free from the ventilator for over 48 hours.