Studies of Neuroendocrine and Energy Metabolism in Patients With Eating Disorders - Full Text View

Sponsor:	National Taiwan University Hospital
Information provided by:	National Taiwan University Hospital
ClinicalTrials.gov Identifier:	NCT00631605

Purpose

This study aims to investigate neuroendocrine, autonomic functioning, and energy metabolism in patients with eating disorder and their relationships with psychopathology of eating disorders (eating patterns, depression, and personality) in these patients.

Condition
Anorexia Nervosa Bulimia Nervosa

Study Type:	Observational
Study Design:	Case Control, Cross-Sectional
Official Title:	Studies of Neuroendocrine and Energy Metabolism in Patients With Eating Disorders

Resource links provided by NLM:

MedlinePlus related topics: Eating Disorders

U.S. FDA Resources

Further study details as provided by National Taiwan University Hospital:

Biospecimen Retention: Samples Without DNA

Biospecimen Description:

serum

Enrollment:	112
Study Start Date:	May 2007
Study Completion Date:	January 2009
Primary Completion Date:	January 2009 (Final data collection date for primary outcome measure)

Groups/Cohorts
1
2

Detailed Description:

The study subjects include female patients with DSM-IV diagnosis of AN (n = 30), BN (n = 60) and age-controled normal subjects (n = 30). They will receive a clinical interview and are asked to complete several self-administered questionnaires which included eating-related questionnaires, general psychological functioning scales and personality scales. After overnight fast, each subject undergoes a blood sample collection for neuroendocrine examination, body composition examination using BIA method, basal metabolic rate measurement by indirect calorimetry, and ECG in the morning between 0800 and 0900. Clinical patients would be asked to repeat filling the self-rating scales, weight and body fat measurement, as well as blood drawing again 2 months after treatment.

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

patients with eating disorders and normal controls

Criteria

Inclusion Criteria:

Subjects who fulfilled DSM-IV diagnosis of anorexia nervosa or bulimia nervosa
Normal controls

Exclusion Criteria:

Any major psychiatric disorders
Use of psychoactive medications
Drug and alcohol abuse
Medical problems (cardiovascular condition and endocrine disorders)

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00631605

Locations

Taiwan
National Taiwan University Hospital
Taipei, Taiwan

Sponsors and Collaborators

National Taiwan University Hospital

Investigators

Principal Investigator:

Mei-Chih Tseng, MD, Msc

National Taiwan University Hospital

More Information

No publications provided

Responsible Party:	National Taiwan University Hospital ( Mei-Chih Tseng/Attending psychiatrist )
Study ID Numbers:	200705061R
Study First Received:	March 3, 2008
Last Updated:	March 1, 2009
ClinicalTrials.gov Identifier:	NCT00631605 History of Changes
Health Authority:	Taiwan: Department of Health

Keywords provided by National Taiwan University Hospital:

eating disorders
ghrelin
leptin
BIA

Additional relevant MeSH terms:

Signs and Symptoms
Bulimia Nervosa
Signs and Symptoms, Digestive
Mental Disorders

Bulimia
Anorexia Nervosa
Eating Disorders
Hyperphagia

ClinicalTrials.gov processed this record on November 09, 2009