Studies of Neuroendocrine and Energy Metabolism in Patients With Eating Disorders - Full Text View

Purpose

This study aims to investigate neuroendocrine and energy metabolism in patients with eating disorder and their relationships with psychopathology of eating disorders (eating patterns, depression, and personality) in these patients.

Condition

Anorexia Nervosa
Bulimia Nervosa

MedlinePlus related topics:

Eating Disorders

ChemIDplus related topics:

Leptin Ghrelin

U.S. FDA Resources

Study Type:	Observational
Study Design:	Case Control, Cross-Sectional

Official Title:	Studies of Neuroendocrine and Energy Metabolism in Patients With Eating Disorders

Further study details as provided by National Taiwan University Hospital:

Biospecimen Retention: Samples Without DNA

Biospecimen Description:

serum

Estimated Enrollment:	120
Study Start Date:	May 2007
Estimated Study Completion Date:	January 2009
Estimated Primary Completion Date:	January 2009 (Final data collection date for primary outcome measure)

Groups/Cohorts

1

2

Detailed Description:

The study subjects include female patients with DSM-IV diagnosis of AN (n = 30), BN (n = 60) and age-matched control subjects (n = 30). They will receive a clinical interview and are asked to complete several self-administered questionnaires which included eating-related questionnaires, general psychological functioning scales and personality scales. After overnight fast, each subject undergoes a blood sample collection for neuroendocrine examination, body composition examination using BIA method, and basal metabolic rate measurement by indirect calorimetry in the morning between 0800 and 0900. Clinical patients would be asked to repeat filling the self-rating scales, weight and body fat measurement, as well as blood drawing again 2 months after treatment.

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

patients with eating disorders and normal controls

Criteria

Inclusion Criteria:

Subjects who fulfilled DSM-IV diagnosis of anorexia nervosa or bulimia nervosa
Normal controls

Exclusion Criteria:

Any major psychiatric disorders
Use of psychoactive medications
Drug and alcohol abuse
Medical problems (cardiovascular condition and endocrine disorders)

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00631605

Contacts


Contact: Mei-Chih Tseng, MD, Msc	886-2-2312-3456 ext 6788	mctseng@ntu.edu.tw

Locations


Taiwan
	National Taiwan University Hospital	Recruiting
	Taipei, Taiwan
	Contact: Mei-Chih Tseng, MD, Msc 886-2-2312-3456 ext 6788 mctseng@ntu.edu.tw
	Principal Investigator: Mei-Chih Tseng, MD, Msc

Sponsors and Collaborators

National Taiwan University Hospital

Investigators


Principal Investigator:	Mei-Chih Tseng, MD, Msc	National Taiwan University Hospital

More Information

Responsible Party:	National Taiwan University Hospital ( Mei-Chih Tseng/Attending psychiatrist )
Study ID Numbers:	200705061R
First Received:	March 3, 2008
Last Updated:	March 7, 2008
ClinicalTrials.gov Identifier:	NCT00631605
Health Authority:	Taiwan: Department of Health

Keywords provided by National Taiwan University Hospital:

eating disorders

ghrelin

leptin

BIA

Study placed in the following topic categories:

Bulimia Nervosa

Mental Disorders

Bulimia

Anorexia

Anorexia Nervosa

Eating Disorders

ClinicalTrials.gov processed this record on September 05, 2008

Sponsored by:	National Taiwan University Hospital
Information provided by:	National Taiwan University Hospital
ClinicalTrials.gov Identifier:	NCT00631605