A Spinal Functional Magnetic Resonance Imagine (fMRI) Study of Resting-State, Motor Task and Acupoint Stimulation

This study has been completed.
Sponsor:
Collaborators:
Ministry of Finance,China
Capital Medical University
Information provided by:
China Rehabilitation Research Center
ClinicalTrials.gov Identifier:
NCT00629655
First received: February 27, 2008
Last updated: June 4, 2009
Last verified: June 2009
  Purpose

The spinal cord is a very important part of the central nervous system. fMRI can be applied to observe functional status of the human spinal cord. Under different conditions, the investigators will see different types of fMRI signals within the spinal cord. In resting state, the investigators might see active/inactive signals, too.


Condition Intervention
Cerebral Infarction
Other: motor task, sensory stimulation

Study Type: Observational
Study Design: Time Perspective: Cross-Sectional
Official Title: A Spinal fMRI Study of Resting-State, Motor Task and Acupoint Stimulation

Resource links provided by NLM:


Further study details as provided by China Rehabilitation Research Center:

Primary Outcome Measures:
  • fMRI [ Time Frame: one day ] [ Designated as safety issue: No ]

Enrollment: 22
Study Start Date: February 2008
Study Completion Date: April 2009
Primary Completion Date: April 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
1
healthy people, male
Other: motor task, sensory stimulation

motor task: finger tapping, simple type and complex type

sensory stimulation: electric or tactile stimulation

Other Names:
  • group 1:healthy people
  • group 2:patients with cerebral infarction,chronic stage
2
male patients with cerebral infarction, chronic stage
Other: motor task, sensory stimulation

motor task: finger tapping, simple type and complex type

sensory stimulation: electric or tactile stimulation

Other Names:
  • group 1:healthy people
  • group 2:patients with cerebral infarction,chronic stage

  Eligibility

Ages Eligible for Study:   18 Years to 45 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

group 1: male residents of Beijing group 2: male stroke patients of Beijing Boai hospital

Criteria

Inclusion Criteria (for healthy people):

  • Chinese male residents
  • right handed
  • no history of psychological/psychotic problems
  • no history of important diseases

Exclusion Criteria (for healthy people):

  • with factors which make subjects unsuitable to receive MR examination
  • history of important diseases

Inclusion Criteria (for patients):

  • Chinese male patients with ischemic stroke (CT/MRI scan confirmed)
  • right handed
  • at least 1.5 months from onset of stroke
  • ability to follow complex commands

Exclusion Criteria (for patients):

  • hemodynamic instability
  • history of dementia
  • inability to give consent because of impaired cognition or receptive aphasia
  • diseases in spine/spinal cord
  • with factors which make subjects unsuitable to receive MR examination
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00629655

Locations
China, Beijing
Beijing Boai Hospital
Beijing, Beijing, China, 100068
Sponsors and Collaborators
China Rehabilitation Research Center
Ministry of Finance,China
Capital Medical University
Investigators
Principal Investigator: Pengxu Wei, Master China Rehabilitation Research Center
  More Information

No publications provided

Responsible Party: Pengxu Wei, China Rehabilitation Research Center
ClinicalTrials.gov Identifier: NCT00629655     History of Changes
Other Study ID Numbers: 2007CZ-4
Study First Received: February 27, 2008
Last Updated: June 4, 2009
Health Authority: China: Ministry of Health

Keywords provided by China Rehabilitation Research Center:
fMRI
spinal cord
human
health
cerebral infarction
healthy

Additional relevant MeSH terms:
Cerebral Infarction
Stroke
Infarction
Brain Infarction
Brain Ischemia
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases
Ischemia
Pathologic Processes
Necrosis

ClinicalTrials.gov processed this record on July 23, 2014