Organization in Acute Atrial Fibrillation Post Open Heart Surgery (A-Fib)

This study is enrolling participants by invitation only.
Sponsor:
Information provided by:
State University of New York - Upstate Medical University
ClinicalTrials.gov Identifier:
NCT00614107
First received: January 30, 2008
Last updated: February 12, 2008
Last verified: January 2008
  Purpose

A form of irregular heart rate called, Atrial Fibrillation (AF) is a major clinical problem. It afflicts about 2 million Americans and is the single largest heart related cause of stroke. However, despite 120 years of speculation and research, the mechanisms that cause AF are poorly understood. Acute AF is also the most common irregular heart rate after open-heart surgery in patients. This is seen in as many as 30% of such patients and often results in a longer hospital stay.

In this study we would like to study the pattern of atrial fibrosis (scar tissue in the heart) and an associated blood marker (a protein called pro-collagen-1) in those patients concurrently having open heart surgery.


Condition
Atrial Fibrillation

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Organization in Acute Atrial Fibrillation Post Open Heart Surgery

Resource links provided by NLM:


Further study details as provided by State University of New York - Upstate Medical University:

Biospecimen Retention:   Samples With DNA

Tissue sample for the right and left sid eof the heart.


Enrollment: 75
Study Start Date: January 2008
Estimated Study Completion Date: January 2009
Estimated Primary Completion Date: January 2009 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   18 Years to 79 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Any person over 18 years having an elective valve, CABG or combination procedure

Criteria

Inclusion Criteria:

  1. 18 years of age, Male or Female
  2. Able to provide consent
  3. Cardiac surgery, CABG of Valve replacement or repair.

Exclusion Criteria:

  1. If AF terminates within 1 hour of initiation.
  2. If the patient undergoes electrical cardioversion and/or receives digitalis within the first hour of inclusion.
  3. If the patients and/or their family or the primary caregiver choose to be excluded from the study anytime, even after the initial 24-hour period.
  4. If the patient expires within 1 hour of inclusion into the study. -
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00614107

Locations
United States, New York
SUNY Upstate Medical University
Syracuse, New York, United States, 13210
Sponsors and Collaborators
State University of New York - Upstate Medical University
  More Information

No publications provided

Responsible Party: Gregory Fink, SUNY Upstate Medical UNiversity
ClinicalTrials.gov Identifier: NCT00614107     History of Changes
Other Study ID Numbers: 5301UMU
Study First Received: January 30, 2008
Last Updated: February 12, 2008
Health Authority: United States: Institutional Review Board

Keywords provided by State University of New York - Upstate Medical University:
Atrial Fibrillation post open heart surgery

Additional relevant MeSH terms:
Atrial Fibrillation
Arrhythmias, Cardiac
Cardiovascular Diseases
Heart Diseases
Pathologic Processes

ClinicalTrials.gov processed this record on October 30, 2014