Magnetic Resonance Imaging and Spectroscopy at High Field

This study has been withdrawn prior to enrollment.
Sponsor:
Information provided by (Responsible Party):
Min-Ying (Lydia) Su, University of California, Irvine
ClinicalTrials.gov Identifier:
NCT00611013
First received: January 12, 2008
Last updated: June 19, 2013
Last verified: June 2013
  Purpose

Evaluating novel MR imaging techniques on volunteers.


Condition Intervention
Healthy
Device: Magnetic Resonance Imaging

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Basic Science
Official Title: Magnetic Resonance Imaging and Spectroscopy at High Field

Resource links provided by NLM:


Further study details as provided by University of California, Irvine:

Primary Outcome Measures:
  • General purpose novel magnetic resonance imaging contrasts, developments for improved magnetic resonance image quality [ Time Frame: 10 years ] [ Designated as safety issue: No ]

Enrollment: 0
Study Start Date: June 2002
Estimated Primary Completion Date: July 2012 (Final data collection date for primary outcome measure)
Intervention Details:
    Device: Magnetic Resonance Imaging
    Some participants may receive MRI contrast agent, 0.1 mmol/kg
Detailed Description:

The aim of this study is twofold. The first aim is to evaluate new MRI techniques developed by the investigators of this protocol on human volunteers. The second aim is to assist other investigators who need to use MR images obtained on this device for their own research. MR images and/or spectroscopy data will be acquired from the participants in this protocol.

  Eligibility

Ages Eligible for Study:   18 Years to 90 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Healthy normal volunteers for imaging protocol optimization.

Exclusion Criteria:

  • Patients with implanted surgical clips (hemostatic clips) or other ferromagnetic material,
  • Patients engaged in occupations or activities which may cause accidental lodging of ferromagnetic materials, or who may have imbedded metal fragments from military activities,
  • Patients with permanent (tattoo) eye-liner or with facial make-up (severe eye irritation has been reported),
  • Patients with compromised thermoregulatory systems (e.g. certain cancer patients),
  • Patients with metallic implants, because they may cause artifacts in diagnostic images due to magnetic field distortion,
  • Patients with implanted prosthetic heart valves,
  • Patients with pacemakers, neuro-stimulation devices,
  • Pregnant patients (the safety of magnetic resonance examination has not been completely established for embryos and fetuses),
  • Subjects who have received orthodontic work involving ferromagnetic materials,
  • Subjects who have claustrophobia, and
  • The patients unwilling to participate in the study or fail to sign the consent form.
  • Subjects who are pregnant or breast-feeding will be excluded from the contrast enhanced MRI studies.
  • Subjects who had allergic response to contrast agents previously will be excluded from contrast enhanced MRI studies.
  • Subjects with known history of asthma, allergic conditions, severe renal insufficiency, sickle cell anemia, chronic hemolytic anemia, gastrointestinal disorders will also be excluded from contrast enhanced MRI studies.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00611013

Locations
United States, California
Center for Functional Onco-Imaging, University of California
Irvine, California, United States, 92697
Sponsors and Collaborators
University of California, Irvine
Investigators
Principal Investigator: Lutfi T Muftuler, Ph.D. University of California, Irvine
  More Information

No publications provided

Responsible Party: Min-Ying (Lydia) Su, Professor, University of California, Irvine
ClinicalTrials.gov Identifier: NCT00611013     History of Changes
Other Study ID Numbers: UCI-HS-2002-2611
Study First Received: January 12, 2008
Last Updated: June 19, 2013
Health Authority: United States: Institutional Review Board

Keywords provided by University of California, Irvine:
Development of multi-purpose novel imaging protocols

ClinicalTrials.gov processed this record on October 01, 2014