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| Sponsor: | Jyväskylä Central Hospital |
|---|---|
| Information provided by: | Jyväskylä Central Hospital |
| ClinicalTrials.gov Identifier: | NCT00605124 |
Purpose
Total knee arthroplasty (TKA) is performed more than 7.000 times a year in Finland most often for osteoarthritis (OA). While pain is predictably reduced, function does not typically ever reach that of age-matched, uninjured subjects. Quadriceps weakness has been implicated in the development and progression of knee OA and is a significant problem after TKA. Advance to return to normal daily activities is not sufficient to restore knee function or quadriceps strength after TKA.
The aim of this study is to assess the effectiveness of progressive exercise program restoring knee strength, mobility and improving the functional outcome after primary TKA.
| Condition | Intervention |
|---|---|
|
Osteoarthritis |
Other: progressive exercise |
| Study Type: | Interventional |
| Study Design: | Randomized, Single Blind (Outcomes Assessor), Parallel Assignment, Efficacy Study |
| Official Title: | Progressive Exercise After Total Knee Arthroplasty: a Randomised Controlled Trial |
| Estimated Enrollment: | 120 |
| Study Start Date: | January 2008 |
| Estimated Study Completion Date: | January 2011 |
| Estimated Primary Completion Date: | January 2010 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
1: Experimental
1: progressive exercise
|
Other: progressive exercise
home-based exercise program, tree exercise sessions weekly, check-up visits every third month
|
Many studies have shown, that after TKA pain decreased significantly, but muscle strength of the operated knee did not recover and may stay under the preoperative level. To find out the effects of progressive exercise program we will perform 6 weeks after TKA a randomized clinical trial of lower extremity strength training using two subgroups of people: traditional exercise group and progressive exercise group.
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Contact: Jari Ylinen, MD, Phd | 358 14 2691145 | jari.ylinen@ksshp.fi |
| Finland | |
| Ceneral Finland Health Care District | Recruiting |
| Jyväskylä, Finland, FIN-40620 | |
| Contact: Jari Ylinen, MD, PhD 358 14 2691145 jari.ylinen@ksshp.fi | |
| Study Director: | Jari Ylinen, MD, PhD | Central Finland Health Care District |
| Study Chair: | Arja Häkkinen, PhD, Professor | Central Finland Health Care District |
| Principal Investigator: | Petri Salo, M.Sc. | Central Finland Health Care District |
| Principal Investigator: | Mirja Vuorenmaa, M.Sc. | Central Finland Health Care District |
| Study Chair: | Maija Pesola, MD | Central Finland Health Care District |
More Information
| Responsible Party: | Jyväskylä Central Hospital ( Jari Ylinen MD, PhD ) |
| Study ID Numbers: | KSSHP Dnro6/2007, KSSHP Dnro6/2007 |
| Study First Received: | January 16, 2008 |
| Last Updated: | January 16, 2008 |
| ClinicalTrials.gov Identifier: | NCT00605124 History of Changes |
| Health Authority: | Finland: Ethics Committee |
|
osteoarthritis knee total knee arthroplasty exercise |
|
Musculoskeletal Diseases Osteoarthritis Joint Diseases Arthritis Rheumatic Diseases |