Cardiac AResT And GENEtic (CARTAGENE)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified July 2010 by Institut National de la Santé Et de la Recherche Médicale, France.
Recruitment status was  Recruiting
Sponsor:
Information provided by (Responsible Party):
Institut National de la Santé Et de la Recherche Médicale, France
ClinicalTrials.gov Identifier:
NCT00604149
First received: January 16, 2008
Last updated: September 26, 2012
Last verified: July 2010
  Purpose

Sudden death is a major problem in industrially developed countries. Despite a decline in ischemic heart disease mortality and the progress has been made in resuscitation, treatment of sudden death victims is frequently unsuccessful. the ideal solution would be to prevent the disease process that causes the initial episode of cardiac arrest. Parental sudden death is an independent risk factor for sudden death. So, detect a gene predisposing to sudden death may help provide better identification of subjects at high risk of cardiac arrest. This research is a genetic study of sudden cardiac death, recruited 2000 subjects in out-of-hospital cardiac arrest.


Condition
Out-of-hospital Cardiac Arrest

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Etude Multicentrique en Population de la susceptibilité génétique à Faire Une Mort Subite

Resource links provided by NLM:


Further study details as provided by Institut National de la Santé Et de la Recherche Médicale, France:

Biospecimen Retention:   Samples With DNA

whole blood to obtain DNA


Estimated Enrollment: 2000
Study Start Date: January 2008
Groups/Cohorts
1
case of out-of-hospital cardiac arrest
2
cases of MI
3
controls without coronary disease

  Eligibility

Ages Eligible for Study:   18 Years to 75 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

all subjects in out-of-hospital cardiac arrest and treated by medical mobil emergency medical care

Criteria

Inclusion Criteria:

  • OHCA
  • Aged from 18 to 75 years

Exclusion Criteria:

  • Pregnant
  • People not free
  • Inhospital subjects
  • Death by other disease
  • Violent death
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00604149

Contacts
Contact: Xavier Jouven, PhD, MD 33 1 59 09 36 87 xavier.jouven@egp.aphp.fr

Locations
France
Hôpital Européen Georges Pompidou Recruiting
Paris, France, 75015
Sponsors and Collaborators
Institut National de la Santé Et de la Recherche Médicale, France
Investigators
Principal Investigator: Xavier Jouven, PhD, MD Institut National de la Santé Et de la Recherche Médicale, France
  More Information

No publications provided

Responsible Party: Institut National de la Santé Et de la Recherche Médicale, France
ClinicalTrials.gov Identifier: NCT00604149     History of Changes
Other Study ID Numbers: C07-35, 2007-A01048-45
Study First Received: January 16, 2008
Last Updated: September 26, 2012
Health Authority: France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)

Additional relevant MeSH terms:
Heart Arrest
Out-of-Hospital Cardiac Arrest
Heart Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on July 24, 2014