Exploring the Role of 3T MRI in Gamma Knife Radiosurgery

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2007 by University Health Network, Toronto.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
University Health Network, Toronto
ClinicalTrials.gov Identifier:
NCT00602992
First received: September 19, 2007
Last updated: January 9, 2009
Last verified: September 2007
  Purpose

Gamma Knife radiosurgery is a non-invasive technique for the delivery of a single, high dose of radiation to an intra-cranial target. MRI has an established and central role in the treatment planning process and assessment of response to intracranial radiosurgery. Increasing the field strength of MRI from 1.5T to 3T promises to improve the signal, and in turn the quality of images. However, the technology also introduces new limitations, and the role and safety of 3T MRI in the management of patients receiving radiosurgery has not yet been reported. In this pilot study, we will explore the spatial integrity, and incremental image-guidance utility of 3T MRI in patients receiving radiosurgery. The preliminary data acquired in this study will be instrumental to the judicious design and conduct of subsequent definitive clinical trials. Up to fifty patients will be enrolled in this study.


Condition
Brain Metastases

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Exploring the Role of 3T MRI in Gamma Knife Radiosurgery: A Pilot Study

Further study details as provided by University Health Network, Toronto:

Estimated Enrollment: 50
Study Start Date: August 2006
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Patients who have consented to Gamma Knife radiosurgery.

Criteria

Inclusion Criteria:

  • Patients planned to receive Gamma Knife radiosurgery will be eligible for enrollment on this study.

Exclusion Criteria:

  • Age<18
  • Contra-indications to 3T MRI, such as implanted metal devices or shrapnel.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00602992

Contacts
Contact: Heather A Sharpe, B.Sc. 416-946-4501 ext 3427 heather.sharpe@uhn.on.ca

Locations
Canada, Ontario
Toronto Western Hospital Recruiting
Toronto, Ontario, Canada, M5T 2S8
Contact: Heather Sharpe, B. Sc.    416-946-4501 ext 3427    heather.sharpe@uhn.on.ca   
Principal Investigator: Cynthia Menard, MD         
Sponsors and Collaborators
University Health Network, Toronto
Investigators
Principal Investigator: Cynthia Menard, MD University Health Network, Toronto
  More Information

No publications provided

Responsible Party: Dr. Cynthia Menard, University Health Network
ClinicalTrials.gov Identifier: NCT00602992     History of Changes
Other Study ID Numbers: 06-0427-CE
Study First Received: September 19, 2007
Last Updated: January 9, 2009
Health Authority: Canada: Health Canada

Keywords provided by University Health Network, Toronto:
3T MRI
Gamma Knife Radiosurgery

ClinicalTrials.gov processed this record on September 18, 2014