Homeostatic Sleep Regulation in Older Persons

This study has been completed.
Sponsor:
Collaborator:
Brigham and Women's Hospital
Information provided by:
National Institute on Aging (NIA)
ClinicalTrials.gov Identifier:
NCT00601445
First received: October 24, 2007
Last updated: May 28, 2008
Last verified: May 2008
  Purpose

The purpose of this study is to test the hypothesis that sleep homeostasis, also known as sleep pressure or sleep drive, is different in healthy older and younger individuals.


Condition Intervention
Healthy
Aging
Behavioral: Amount of sleep and wake

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Basic Science
Official Title: Homeostatic Sleep Regulation in Older Persons

Further study details as provided by National Institute on Aging (NIA):

Primary Outcome Measures:
  • Total Sleep Time [ Time Frame: During inpatient study ]

Estimated Enrollment: 58
Study Start Date: September 1999
Study Completion Date: March 2004
Intervention Details:
    Behavioral: Amount of sleep and wake
    4 groups with different patterns of sleep and wake
Detailed Description:

This was an inpatient study of healthy individuals to determine whether homeostatic "sleep drive" effects on sleep change with healthy aging. Sleep, performance, and mood were studied on individuals sleeping different lengths of time and during wake periods of different durations.

  Eligibility

Ages Eligible for Study:   18 Years to 85 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Ages 18-30 and 60-85 years
  • Healthy

Exclusion Criteria:

  • Any medications
  • Sleep Disorder
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00601445

Locations
United States, Massachusetts
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115
Sponsors and Collaborators
Brigham and Women's Hospital
Investigators
Principal Investigator: Elizabeth B Klerman, MD, PhD Brigham and Women's Hospital
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00601445     History of Changes
Other Study ID Numbers: AG0090, P01-AG009975 - Project 4
Study First Received: October 24, 2007
Last Updated: May 28, 2008
Health Authority: United States: Federal Government

Keywords provided by National Institute on Aging (NIA):
Changes in sleep with aging

ClinicalTrials.gov processed this record on September 18, 2014