Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary Adenoma

This study is currently recruiting participants.

Verified by Cedars-Sinai Medical Center, July 2009

First Received: January 11, 2008 Last Updated: July 8, 2009 History of Changes

Sponsor:	Cedars-Sinai Medical Center
Information provided by:	Cedars-Sinai Medical Center
ClinicalTrials.gov Identifier:	NCT00598949

Purpose

The purpose of the study is to determine genetic links among blood-relatives and between spouses of patients with pituitary tumors.

Condition
Pituitary Adenoma

Study Type:	Observational
Study Design:	Family-Based, Prospective
Official Title:	Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary Adenoma

Resource links provided by NLM:

MedlinePlus related topics: Cancer

U.S. FDA Resources

Further study details as provided by Cedars-Sinai Medical Center:

Biospecimen Retention: Samples With DNA

Biospecimen Description:

cell lines are established for future genetic analysis

Estimated Enrollment:	600
Study Start Date:	January 2003
Estimated Primary Completion Date:	December 2009 (Final data collection date for primary outcome measure)

Detailed Description:

The purpose of the family study is to investigate the genetic basis for the development of pituitary tumors by assessing the prevalence of pituitary tumors in relatives of probands with the disease as compared to the prevalence in unrelated spouses sharing a similar environment.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

tertiary referral center

Criteria

Inclusion Criteria:

patients harboring secretory or non-secretory adenomas and/or siblings and/or spouses

Exclusion Criteria:

patient without consenting siblings and/or siblings and/or spouses

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00598949

Contacts

Contact: Vivien Bonert, MD	310-423-2830	Bonertv@cshs.org
Contact: Lori korsakoff, RN	310-423-2411	lori.korsakoff@cshs.org

Locations

United States, California
Cedars-Sinai Medical Center, Pituitary Center	Recruiting
Los Angeles, California, United States, 90048
Contact: Vivien Bonert, MD 310-423-2830 Bonertv@cshs.org
Contact: Lori Korsakoff, RN 310-423-2411 lori.korsakoff@cshs.org

Sponsors and Collaborators

Cedars-Sinai Medical Center

Investigators

Principal Investigator:

Vivian Bonert, MD

Cedars-Sinai Medical Center

More Information

No publications provided

Responsible Party:	Cedars-Sinai Medical Center, Pituitary Center ( Vivien Bonert, MD )
Study ID Numbers:	3765, 3765
Study First Received:	January 11, 2008
Last Updated:	July 8, 2009
ClinicalTrials.gov Identifier:	NCT00598949 History of Changes
Health Authority:	United States: Institutional Review Board

Keywords provided by Cedars-Sinai Medical Center:

pituitary adenoma

Additional relevant MeSH terms:

Pituitary Neoplasms
Pituitary Diseases
Hypothalamic Diseases
Neoplasms by Histologic Type
Nervous System Diseases
Endocrine System Diseases
Central Nervous System Diseases
Central Nervous System Neoplasms
Brain Diseases

Supratentorial Neoplasms
Brain Neoplasms
Neoplasms
Neoplasms by Site
Hypothalamic Neoplasms
Adenoma
Nervous System Neoplasms
Neoplasms, Glandular and Epithelial
Endocrine Gland Neoplasms

ClinicalTrials.gov processed this record on February 08, 2010