Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary Adenoma

This study is currently recruiting participants. (see Contacts and Locations)
Verified December 2010 by Cedars-Sinai Medical Center
Sponsor:
Information provided by:
Cedars-Sinai Medical Center
ClinicalTrials.gov Identifier:
NCT00598949
First received: January 11, 2008
Last updated: December 14, 2010
Last verified: December 2010
  Purpose

The purpose of the study is to determine genetic links among blood-relatives and between spouses of patients with pituitary tumors.


Condition
Pituitary Tumor

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary Adenoma

Resource links provided by NLM:


Further study details as provided by Cedars-Sinai Medical Center:

Biospecimen Retention:   Samples With DNA

cell lines are established for future genetic analysis


Estimated Enrollment: 600
Study Start Date: January 2003
Estimated Primary Completion Date: December 2015 (Final data collection date for primary outcome measure)
Detailed Description:

The purpose of the family study is to investigate the genetic basis for the development of pituitary tumors by assessing the prevalence of pituitary tumors in relatives of probands with the disease as compared to the prevalence in unrelated spouses sharing a similar environment.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

tertiary referral center

Criteria

Inclusion Criteria:

  • patients harboring secretory or non-secretory adenomas and/or siblings and/or spouses

Exclusion Criteria:

  • patient without consenting siblings and/or siblings and/or spouses
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00598949

Contacts
Contact: Billy Gellepis 310-423-3395 Billy.Gellepis@cshs.org
Contact: Lori korsakoff, RN 310-423-2411 lori.korsakoff@cshs.org

Locations
United States, California
Cedars-Sinai Medical Center, Pituitary Center Recruiting
Los Angeles, California, United States, 90048
Contact: Vivien Bonert, MD    310-423-2830    Bonertv@cshs.org   
Contact: Lori Korsakoff, RN    310-423-2411    lori.korsakoff@cshs.org   
Sponsors and Collaborators
Cedars-Sinai Medical Center
Investigators
Principal Investigator: Vivian Bonert, MD Cedars-Sinai Medical Center
  More Information

No publications provided

Responsible Party: Vivien Bonert, MD, Cedars-Sinai Medical Center, Pituitary Center
ClinicalTrials.gov Identifier: NCT00598949     History of Changes
Other Study ID Numbers: 3765, 3765
Study First Received: January 11, 2008
Last Updated: December 14, 2010
Health Authority: United States: Institutional Review Board

Keywords provided by Cedars-Sinai Medical Center:
Pituitary
Adenoma
Tumor
Acromegaly
Prolactinoma
Cushing's

Additional relevant MeSH terms:
Pituitary Neoplasms
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Neoplasms
Endocrine Gland Neoplasms
Neoplasms by Site
Hypothalamic Neoplasms
Supratentorial Neoplasms
Brain Neoplasms
Central Nervous System Neoplasms
Nervous System Neoplasms
Pituitary Diseases
Adenoma
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Hypothalamic Diseases
Endocrine System Diseases

ClinicalTrials.gov processed this record on August 26, 2014