Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary Adenoma

This study is currently recruiting participants.

Verified December 2010 by Cedars-Sinai Medical Center

First Received on January 11, 2008. Last Updated on December 14, 2010 History of Changes

Sponsor:	Cedars-Sinai Medical Center
Information provided by:	Cedars-Sinai Medical Center
ClinicalTrials.gov Identifier:	NCT00598949

Purpose

The purpose of the study is to determine genetic links among blood-relatives and between spouses of patients with pituitary tumors.

Condition
Pituitary Tumor

Study Type:	Observational
Study Design:	Observational Model: Case Control Time Perspective: Prospective
Official Title:	Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary Adenoma

Resource links provided by NLM:

MedlinePlus related topics: Cancer Pituitary Tumors

U.S. FDA Resources

Further study details as provided by Cedars-Sinai Medical Center:

Biospecimen Retention: Samples With DNA

cell lines are established for future genetic analysis

Estimated Enrollment:	600
Study Start Date:	January 2003
Estimated Primary Completion Date:	December 2015 (Final data collection date for primary outcome measure)

Detailed Description:

The purpose of the family study is to investigate the genetic basis for the development of pituitary tumors by assessing the prevalence of pituitary tumors in relatives of probands with the disease as compared to the prevalence in unrelated spouses sharing a similar environment.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

tertiary referral center

Criteria

Inclusion Criteria:

patients harboring secretory or non-secretory adenomas and/or siblings and/or spouses

Exclusion Criteria:

patient without consenting siblings and/or siblings and/or spouses

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00598949

Contacts

Contact: Billy Gellepis	310-423-3395	Billy.Gellepis@cshs.org
Contact: Lori korsakoff, RN	310-423-2411	lori.korsakoff@cshs.org

Locations

United States, California
Cedars-Sinai Medical Center, Pituitary Center	Recruiting
Los Angeles, California, United States, 90048
Contact: Vivien Bonert, MD 310-423-2830 Bonertv@cshs.org
Contact: Lori Korsakoff, RN 310-423-2411 lori.korsakoff@cshs.org

Sponsors and Collaborators

Cedars-Sinai Medical Center

Investigators

Principal Investigator:

Vivian Bonert, MD

Cedars-Sinai Medical Center

More Information

No publications provided

Responsible Party:	Vivien Bonert, MD, Cedars-Sinai Medical Center, Pituitary Center
ClinicalTrials.gov Identifier:	NCT00598949 History of Changes
Other Study ID Numbers:	3765, 3765
Study First Received:	January 11, 2008
Last Updated:	December 14, 2010
Health Authority:	United States: Institutional Review Board

Keywords provided by Cedars-Sinai Medical Center:

Pituitary
Adenoma
Tumor

Acromegaly
Prolactinoma
Cushing's

Additional relevant MeSH terms:

Adenoma
Pituitary Neoplasms
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Neoplasms
Endocrine Gland Neoplasms
Neoplasms by Site
Hypothalamic Neoplasms
Supratentorial Neoplasms

Brain Neoplasms
Central Nervous System Neoplasms
Nervous System Neoplasms
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Hypothalamic Diseases
Pituitary Diseases
Endocrine System Diseases

ClinicalTrials.gov processed this record on May 22, 2012