Inclusion Criteria:

• Have a cataract sufficiently opaque/mature/brunescent that, in the surgeon's assessment,a dye could facilitate surgery;
• Be aged at least 18 years old at the time of enrollment;
• Be able to tolerate a surgical procedure for up to 3 hours;
• Be in a medical condition suitable for cataract surgery;
• Able and willing to participate in study examinations and visit schedule; and
• Understand and freely consent to participate in the study.

Exclusion Criteria:

• In either eye, ocular infection or inflammation within the past 3 months;
• Known allergy to BBG 250;
• Uncontrolled intercurrent diseases including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, or cardiac arrhythmia;
• Active treatment for cancer or systemic infection within the past month;
• Active treatment with systemic corticosteroids within the past month;
• Previous participation in this Study for the contralateral eye;
• Participation in another clinical trial involving an investigational therapeutic during the past 30 days or 5.5 half-lives (if applicable), whichever is longer;
• Unwillingness to participate in the study or inability to give informed consent; or
• Any medical condition that in the opinion of the Investigator may compromise the research subject's safety or ability to participate in the study.