Ramanspectroscopy in Barrett's Esophagus

This study has been completed.
Sponsor:
Collaborator:
Information provided by:
Mayo Clinic
ClinicalTrials.gov Identifier:
NCT00588575
First received: December 22, 2007
Last updated: September 14, 2009
Last verified: September 2009
  Purpose

This study is being done to see if a new device, called near-infrared Raman spectroscopy, can provide similar information as that obtained from taking biopsies of the lining of your Barrett's esophagus


Condition
Barrett's Esophagus

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: In-Vivo Raman Spectroscopy of Barrett's Esophagus

Further study details as provided by Mayo Clinic:

Biospecimen Retention:   Samples Without DNA

esophageal biopsy


Enrollment: 119
Study Start Date: October 2004
Study Completion Date: October 2007
Primary Completion Date: May 2007 (Final data collection date for primary outcome measure)
Detailed Description:

In the search for means to enhance the surveillance of BE, optical spectroscopy is emerging as a candidate with high potential. Optical spectroscopic techniques measure specific light-tissue interactions, such as fluorescence, elastic scattering, and Raman (inelastic) scattering, which provide objective and quantitative diagnostic information about the molecular and/or structural status of tissue. Moreover, optical spectroscopy has the capacity to identify tissue pathology in situ in a rapid and non-destructive fashion. Among the optical spectroscopic techniques, near-infrared Raman spectroscopy (NIRS) is particularly promising because of the wealth of molecular-specific information contained in its spectra

  Eligibility

Ages Eligible for Study:   18 Years to 85 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Barrett's esophagus surveillance

Criteria

Inclusion Criteria:

  • Closed to further enrollment
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00588575

Locations
United States, Minnesota
Mayo Clinic
Rochester, Minnesota, United States, 55905
Sponsors and Collaborators
Mayo Clinic
Investigators
Principal Investigator: Louis M Wongkeesong, MD Mayo Clinic
  More Information

Additional Information:
No publications provided

Responsible Party: Louis Michel WongkeeSong, Mayo Clinic
ClinicalTrials.gov Identifier: NCT00588575     History of Changes
Other Study ID Numbers: 1999-04 00, DK67148, Raman
Study First Received: December 22, 2007
Last Updated: September 14, 2009
Health Authority: United States: Institutional Review Board

Keywords provided by Mayo Clinic:
Barrett's Esophagus

Additional relevant MeSH terms:
Barrett Esophagus
Digestive System Abnormalities
Digestive System Diseases
Esophageal Diseases
Gastrointestinal Diseases

ClinicalTrials.gov processed this record on July 23, 2014