Improving Walking in Older Adults With Knee Osteoarthritis

This study has been completed.
Sponsor:
Collaborator:
Information provided by:
University of Iowa
ClinicalTrials.gov Identifier:
NCT00583245
First received: December 20, 2007
Last updated: June 24, 2010
Last verified: June 2010
  Purpose

Knee osteoarthritis (OA) accounts for a significant proportion of mobility limitations and is one of the most disabling problems facing the growing population of older adults. The long-term objective of this research is to reduce disablement of older adults with symptomatic knee OA. The principle of specificity of training indicates that exercises that closely approximate the goal functional activity are most effective in improving physical performance during that activity. Based on this principle, the specific aim of this pilot study is to design a patient-specific gait training intervention using analysis of compensatory joint moments and energy expenditure. Successful completion will inform rehabilitation for maintaining or improving mobility as well as explore the mechanism of effect.


Condition Intervention
Knee Osteoarthritis
Other: Gait Training

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Optimizing Mobility in Older Adults With Knee Osteoarthritis

Resource links provided by NLM:


Further study details as provided by University of Iowa:

Primary Outcome Measures:
  • Changes in functional limitation assessed by the A) Summary Performance Score which includes balance tests, timed 4-meter walk, and timed chair stand test B) Timed stair climb C) Late Life Function and Disability Instrument (LLFDI) Questionnaire [ Time Frame: 12 weeks ] [ Designated as safety issue: No ]
  • Changes in the disability measure, a timed 400 meter walk [ Time Frame: 12 Weeks ] [ Designated as safety issue: No ]
  • Changes in impairments assessed using the Knee and Osteoarthritis Outcome Score (KOOS) questionnaire [ Time Frame: 12 Weeks ] [ Designated as safety issue: No ]

Enrollment: 27
Study Start Date: December 2007
Study Completion Date: December 2009
Primary Completion Date: September 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
Gait training
Other: Gait Training
Gait training with physical therapist 2/week for 3 months

  Eligibility

Ages Eligible for Study:   60 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Symptomatic knee osteoarthritis (knee osteoarthritis diagnosed by x-ray and frequent knee symptoms)
  • Age 60 or older

Exclusion Criteria:

  • acute or terminal illness
  • unstable cardiovascular condition or other medical conditions that may impair ability to participate such as pulmonary disease requiring the use of supplemental oxygen, neurological disease that affects gait, or lower limb musculoskeletal surgery in the past 6 months.
  • Bilateral knee replacement
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00583245

Locations
United States, Iowa
University of Iowa
Iowa City, Iowa, United States, 52242
Sponsors and Collaborators
University of Iowa
Investigators
Principal Investigator: Neil Segal, MD University of Iowa
  More Information

No publications provided

Responsible Party: Neil Segal, MD, The University of Iowa
ClinicalTrials.gov Identifier: NCT00583245     History of Changes
Other Study ID Numbers: NCT00331110, 1K23AG030945-01
Study First Received: December 20, 2007
Last Updated: June 24, 2010
Health Authority: United States: Institutional Review Board

Keywords provided by University of Iowa:
Osteoarthritis
Gait training
Knee pain
Rehabilitation
Physical Therapy

Additional relevant MeSH terms:
Osteoarthritis
Osteoarthritis, Knee
Arthritis
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases

ClinicalTrials.gov processed this record on October 01, 2014