Prevalence of Lymphoma in IBD

The recruitment status of this study is unknown because the information has not been verified recently.
Verified December 2007 by Indiana University.
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
Indiana University
ClinicalTrials.gov Identifier:
NCT00577538
First received: December 19, 2007
Last updated: NA
Last verified: December 2007
History: No changes posted
  Purpose

Patients with inflammatory bowel disease (IBD) may be at increased risk of lymphoma. The majority of lymphomas in patients with IBD occur in areas of active inflammation. The relationship between IBD and lymphoproliferative disease is however unclear, since both chronic inflammation as well as medications used to treat IBD (especially immunosuppressives - Azathioprine or 6-MP - and anti-TNF alpha agents) have been associated with increased risk of lymphoma. We plan to study the association between IBD and lymphoma in a large, mixed, community based and referral population from the IBD database at Indiana University.


Condition
Lymphoma
Inflammatory Bowel Disease

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Retrospective
Official Title: Prevalence and Risk Factor for Lymphoproliferative Disease in Patients With Inflammatory Bowel Disease

Resource links provided by NLM:


Further study details as provided by Indiana University:

Estimated Enrollment: 6
Study Start Date: April 2006
Estimated Study Completion Date: December 2007

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Patients diagnosed with both Inflammatory bowel disease and lymphoma over the last 30 years.

Criteria

Inclusion Criteria:

  • Inflammatory Bowel disease
  • Lymphoma
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00577538

Locations
United States, Indiana
Indiana University Medical Center
Indianapolis, Indiana, United States, 46202
Sponsors and Collaborators
Indiana University
Investigators
Principal Investigator: Michael V. Chiorean, M.D. Indiana University
  More Information

No publications provided

Responsible Party: Michael Chiorean M.D., Indiana University
ClinicalTrials.gov Identifier: NCT00577538     History of Changes
Other Study ID Numbers: 060358, IRB# 0603-58
Study First Received: December 19, 2007
Last Updated: December 19, 2007
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Inflammatory Bowel Diseases
Intestinal Diseases
Lymphoma
Lymphoproliferative Disorders
Gastroenteritis
Gastrointestinal Diseases
Digestive System Diseases
Neoplasms by Histologic Type
Neoplasms
Lymphatic Diseases
Immunoproliferative Disorders
Immune System Diseases

ClinicalTrials.gov processed this record on April 15, 2014