Validation of the Gated Blood Pool SPECT: ERNA vs 3D Echo
Recruitment status was Recruiting
This research study is designed to evaluate the accuracy of the techniques that are used to analyze heart function. The main purpose of this study is to analyze and compare three different methods of assessment of regional and overall heart function.
Congestive Heart Failure
Ventricular Function, Left
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Validation of the Gated Blood Pool SPECT: Comparison to ERNA and 3-dimensional Echocardiography.|
- 2D echo provides a good estimate of regional LV function but if done with 3D analysis can provide a good estimate of global LV function and volumes. The quality of 3DE can be further improved by use of IV contrast which is FDA approved. [ Time Frame: 1 day ] [ Designated as safety issue: No ]
|Study Start Date:||February 2005|
|Estimated Study Completion Date:||January 2011|
Patients being referred for the routine Equilibrium Radionuclide Angiocardiography (ERNA) for assessment of their left ventricular function will be asked to participate in the study. All patients will be asked to sign the consent form. Patients will be given a choice to participate in either or both studies (i.e. ERNA plus ACGBS or ERNA plus ACGBS and 3 DE).
The purpose of the present study is to establish the reproducibility and to validate gated blood pool SPECT imaging with application of attenuation correction (ACGBS) in evaluation of left ventricular regional and global function and volumes, by direct comparison with Equilibrium Radionuclide Angiocardiography (ERNA) and 3-dimensional ECHO (3DE).
|Contact: Carol Akirav, MScfirstname.lastname@example.org|
|Contact: Albert J Sinusas, MD||203-785-3155|
|United States, Connecticut|
|Yale New Haven Hospital||Recruiting|
|New Haven, Connecticut, United States, 06520|
|Contact: Carol Akirav, MSc 203-785-2429 email@example.com|
|Contact: Albert J Sinusas, MD 203-785-3155 firstname.lastname@example.org|
|Sub-Investigator: Robin Doyle, MD|
|Sub-Investigator: Frans Walkers, MD|
|Sub-Investigator: Robert McNamara, MD|
|Principal Investigator:||Albert J Sinusas, MD||Yale University|