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Efficacy of Plyometrics to Increase Bone Mass in Men With Osteopenia

This study is currently recruiting participants.
Verified September 2011 by University of Missouri-Columbia
Sponsor:
Collaborator:
National Institutes of Health (NIH)
Information provided by (Responsible Party):
Pamela Hinton, University of Missouri-Columbia
ClinicalTrials.gov Identifier:
NCT00572104
First received: December 10, 2007
Last updated: September 20, 2011
Last verified: September 2011
History of Changes
  Purpose

This study will compare the ability of two types of long term (12 months) weight-bearing exercise treatments (1. high-intensity jumping and 2. weight lifting) to increase bone mass of the total body, spine and hip in physically active men with osteopenia.


Condition Intervention
Osteopenia
 Other: exercise intervention

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Efficacy of Plyometrics to Increase Bone Mass in Men With Osteopenia

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by University of Missouri-Columbia:

Primary Outcome Measures:
  • Bone Mineral Density [ Time Frame: 12 months ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Serum markers of bone turnover [ Time Frame: 3 months ] [ Designated as safety issue: No ]
  • Serum hormones regulating bone turnover [ Time Frame: 3 months ] [ Designated as safety issue: No ]

Estimated Enrollment: 40
Study Start Date: January 2008
Estimated Study Completion Date: June 2013
Estimated Primary Completion Date: June 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
12 month resistance exercise training
 Other: exercise intervention
12 month training intervention of either plyometrics or weight resistance exercise.
Other Name: All participants receive a daily calcium and vitamin D supplement
Experimental: 2
12 month plyometric exercise training
 Other: exercise intervention
12 month training intervention of either plyometrics or weight resistance exercise.
Other Name: All participants receive a daily calcium and vitamin D supplement

  Eligibility

Ages Eligible for Study:   25 Years to 60 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Male
  • Age 25-60 years
  • No symptoms of disease
  • Currently participating in cycling activities an average of 4 hr/wk for the previous 24 months
  • Osteopenia of the lumbar spine and/or hip (T score < -1.0 and > -2.5 )

Exclusion Criteria:

  • Medications or supplements that affect bone metabolism or prevent exercise
  • Previous or current medical condition affecting bone health
  • Osteoporosis of the lumbar spine and/or hip (T score > -1.0 or < -2.5)
  • Cardiovascular disease
  • Metallic implants
  • Current smoker
  • Current regular participation in high-intensity resistance training and/or plyometrics
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00572104

Contacts
Contact: Pamela S Hinton 573-882-4137 HintonP@missouri.edu
Contact: Peggy S Nigh 573-882-9917 nighm@health.missouri.edu

Locations
United States, Missouri
University of Missouri-Columbia; McKee Gym Recruiting
Columbia, Missouri, United States, 65211
Sponsors and Collaborators
University of Missouri-Columbia
National Institutes of Health (NIH)
Investigators
Principal Investigator: Pamela S Hinton University of Missouri-Columbia, Department of Nutritional Sciences
  More Information

No publications provided

Responsible Party: Pamela Hinton, Associate Professor of Nutrition and Exercise Physiology, University of Missouri-Columbia
ClinicalTrials.gov Identifier: NCT00572104     History of Changes
Other Study ID Numbers: 1095877
Study First Received: December 10, 2007
Last Updated: September 20, 2011
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Bone Diseases, Metabolic
Bone Diseases
Musculoskeletal Diseases

ClinicalTrials.gov processed this record on May 23, 2013