Agreement Between Venous and Arterial Blood Gas Measurements in the Intensive Care Unit (AVANTI)

This study has been completed.
Sponsor:
Collaborator:
Olive View-UCLA Education & Research Institute
Information provided by:
University of California, Los Angeles
ClinicalTrials.gov Identifier:
NCT00569634
First received: December 6, 2007
Last updated: December 2, 2008
Last verified: December 2008
  Purpose

The purpose of this study is to examine the agreement between venous blood gas and arterial blood gas measurements in patients in the Intensive Care Unit.


Condition Intervention
Acid-Base Balance
Procedure: Venous blood gas analysis

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Diagnostic
Official Title: Agreement Between Venous and Arterial Blood Gas Measurements in the Intensive Care Unit

Further study details as provided by University of California, Los Angeles:

Primary Outcome Measures:
  • Agreement between venous and arterial blood gas measurements of pH, pCO2 and bicarbonate [ Time Frame: Duration of Intensive Care Unit Admission ] [ Designated as safety issue: No ]

Enrollment: 40
Study Start Date: January 2008
Study Completion Date: July 2008
Primary Completion Date: July 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
1 Procedure: Venous blood gas analysis
When an ABG is deemed to be necessary as part of ICU management, a central venous sample will also be obtained with minimum delay (always < 2 minutes) between the samples. The samples will be analyzed by a blood gas analyzer as quickly as possible.

Detailed Description:

Venous blood gas analysis may be an alternative to arterial blood gas analysis for acid-base status, reducing the need for frequent invasive arterial sampling. The objective of this study is to examine the agreement between ABG and VBG samples for all commonly used parameters (pH, pCO2 and bicarbonate) in a pathologically diverse ICU patient population, specifically analyzing multiple paired arterial and venous samples from each patient.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Adult patients 18 years or older
  • Admitted to the Intensive Care Unit (ICU)
  • Determined by their treating clinicians to require both a central venous line and arterial line

Exclusion Criteria:

  • None
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00569634

Sponsors and Collaborators
University of California, Los Angeles
Olive View-UCLA Education & Research Institute
Investigators
Principal Investigator: Richard M Treger, M.D. Olive View-UCLA Education & Research Institute
  More Information

Publications:

Responsible Party: Richard Treger, M.D., Olive View-UCLA Medical Center
ClinicalTrials.gov Identifier: NCT00569634     History of Changes
Other Study ID Numbers: 07H-821001
Study First Received: December 6, 2007
Last Updated: December 2, 2008
Health Authority: United States: Institutional Review Board

Keywords provided by University of California, Los Angeles:
Venous blood gas
Arterial blood gas
pH
pCO2
Bicarbonate

ClinicalTrials.gov processed this record on July 24, 2014