Immunohistochemical & Immunoblot Analysis of NIS (Na+/I-Symporter) in Archival & Frozen Tissue Sample
The goal of this study is to study NIS expression in benign and malignant breast and thyroid samples using archival formalin-fixed paraffin-embedded tissue sections.
Salivary Gland Neoplasms
|Study Design:||Observational Model: Cohort
Time Perspective: Retrospective
|Official Title:||Immunohistochemical & Immunoblot Analysis of NIS (Na+/I-Symporter) in Archival and Frozen Human Tissue Samples|
Cases will be identified from clinic patient medical records and linked to pathology reports. The surgical pathology record number will thus be obtained and used to retrieve the archival blocks and slides. Approximately three representative blocks will be selected and 4-6 four micron thick sections will be cut on a microtome. Cases with limited archived diagnostic material will not be selected nor blocks where there is little materials.
|Study Start Date:||October 2000|
|Estimated Study Completion Date:||December 2016|
|Estimated Primary Completion Date:||December 2016 (Final data collection date for primary outcome measure)|
The objective of the study is to further understanding of proteins that occur in both normal cells and tumor cells and to learn more about certain diseases and potential alternative treatments for these diseases.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00568438
|United States, California|
|Stanford University School of Medicine||Recruiting|
|Stanford, California, United States, 94305|
|Contact: Donna Adelman 650-724-1953 firstname.lastname@example.org|
|Contact: Cancer Clinical Trials Office (650) 498-7061|
|Principal Investigator: Irene L. Wapnir|
|Sub-Investigator: Ralph S. Greco MD|
|Sub-Investigator: Kent W Nowels|
|Principal Investigator:||Irene L. Wapnir||Stanford University|