Evaluating a Web-Based Ventilator Management Educational Program for Clinicians (The Lung Injury Knowledge Network [LINK] Study)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2010 by Sunnybrook Health Sciences Centre.
Recruitment status was  Active, not recruiting
Sponsor:
Collaborator:
Information provided by:
Sunnybrook Health Sciences Centre
ClinicalTrials.gov Identifier:
NCT00542737
First received: October 10, 2007
Last updated: July 9, 2013
Last verified: August 2010
  Purpose

Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a severe lung condition that causes respiratory failure. Individuals with ALI/ARDS often require the use of a respirator or artificial breathing machine, known as a mechanical ventilator, while in an intensive care unit (ICU). Research has shown that lung protective ventilation (LPV), a type of mechanical ventilation technique, is an effective way to reduce the number of deaths due to ALI/ARDS. This study will evaluate the effectiveness of a Web-based educational program that aims to educate ICU clinicians about the use of LPV in patients with ALI/ARDS.


Condition Intervention
Respiratory Distress Syndrome, Adult
Behavioral: Web-Based Educational Program

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Official Title: Improving Ventilator Management and Preventing Injury to Patients With Acute Respiratory Failure

Resource links provided by NLM:


Further study details as provided by Sunnybrook Health Sciences Centre:

Primary Outcome Measures:
  • Percentage of eligible patients with ALI/ARDS who are receiving LPV [ Time Frame: Measured at Month 6 ] [ Designated as safety issue: No ]

Estimated Enrollment: 120
Study Start Date: February 2009
Estimated Study Completion Date: July 2014
Estimated Primary Completion Date: September 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Early Intervention Group Behavioral: Web-Based Educational Program
Participating clinicians at each hospital will access the Web site as often as necessary for a 6-month period. The Web site will contain background and educational information on ALI/ARDS and LPV, including how to recognize ALI/ARDS and how to implement LPV in patients. Scholarly articles and other materials, including a chart to help clinicians determine appropriate ventilator settings for each patient, will be available to download. Clinicians will also be able to email questions to critical care experts.
Active Comparator: Delayed Intervention Group Behavioral: Web-Based Educational Program
Participating clinicians at each hospital will access the Web site as often as necessary for a 6-month period. The Web site will contain background and educational information on ALI/ARDS and LPV, including how to recognize ALI/ARDS and how to implement LPV in patients. Scholarly articles and other materials, including a chart to help clinicians determine appropriate ventilator settings for each patient, will be available to download. Clinicians will also be able to email questions to critical care experts.

Detailed Description:

ALI/ARDS is a life-threatening condition that involves inflammation of the lungs and fluid accumulation in the air sacs, leading to low blood oxygen levels and respiratory failure. Common causes include pneumonia, septic shock, and lung trauma, and most patients require immediate care in an ICU. The main form of treatment for ALI/ARDS is the delivery of oxygen and a continuous level of pressure to the damaged lungs through mechanical ventilation. Each year, 74,500 people die due to ALI/ARDS and 22% of these deaths could be prevented with the use of LPV. LPV is a mechanical ventilation technique in which lower volumes of oxygen are administered. The purpose of this study is to implement and evaluate a Web-based educational program that will provide educational and instructional resources about ALI/ARDS and LPV to ICU clinicians, including physicians, nurses, and respiratory therapists.

Hospitals participating in this study will be randomly assigned to access the Web site at either the beginning of the study period or a later time. Participating clinicians at each hospital will access the Web site as often as necessary for a 6-month period. The Web site will contain background and educational information on ALI/ARDS and LPV, including how to recognize ALI/ARDS and how to implement LPV in patients. Scholarly articles and other materials, including a chart to help clinicians determine appropriate ventilator settings for each patient, will be available to download. Clinicians will also be able to email questions to critical care experts. At the end of the 6-month study period, study staff will compare the number of patients receiving LPV to the number of patients who received LPV prior to the start of the study.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria for Hospitals:

  • Between 10 and 20 ICU beds with 5 to 10 ALI/ARDS patients cared for each month
  • Provide critical care services
  • Keep electronic medical records on ICU patients
  • ICU staff must have access to computers with Intranet or Internet

Inclusion Criteria for Clinicians:

  • Provide care for mechanically ventilated patients in ICUs
  • Willing to participate by viewing Web site

Exclusion Criteria for Hospitals:

  • Cardiac, cardiothoracic, neurosurgical, neonatal, or pediatric ICUs
  • Residents and fellows must provide care to majority of critically ill patients
  • Fewer than 5 to 10 ALI/ARDS patients cared for each month
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00542737

Locations
Canada, Ontario
University of Toronto, Sunnybrook Health Sciences
Toronto, Ontario, Canada, M4N3M5
Sponsors and Collaborators
Sunnybrook Health Sciences Centre
Investigators
Principal Investigator: Gordon D. Rubenfeld, MD University of Toronto, Sunnybrook Health Sciences
  More Information

No publications provided

Responsible Party: Gordon D. Rubenfeld, MD, University of Toronto, Sunnybrook Health Sciences
ClinicalTrials.gov Identifier: NCT00542737     History of Changes
Other Study ID Numbers: 518, R01HL067939, R01 HL067939, GC1# A19846
Study First Received: October 10, 2007
Last Updated: July 9, 2013
Health Authority: United States: Federal Government

Keywords provided by Sunnybrook Health Sciences Centre:
Acute Lung Injury
Acute Respiratory Distress Syndrome
Acute Respiratory Failure
Web-Based Intervention
Lung Preventive Ventilation

Additional relevant MeSH terms:
Respiratory Distress Syndrome, Newborn
Respiratory Distress Syndrome, Adult
Acute Lung Injury
Lung Injury
Respiratory Insufficiency
Wounds and Injuries
Lung Diseases
Respiratory Tract Diseases
Respiration Disorders
Infant, Premature, Diseases
Infant, Newborn, Diseases
Thoracic Injuries

ClinicalTrials.gov processed this record on August 20, 2014