Transient Osteoporosis of Pregnancy: A Possible Peptide Mediator

This study has suspended participant recruitment.
Sponsor:
Information provided by:
Hadassah Medical Organization
ClinicalTrials.gov Identifier:
NCT00541645
First received: October 7, 2007
Last updated: March 17, 2008
Last verified: March 2008
  Purpose

Transient osteoporosis of pregnancy (TOoP) is uncommonly encountered in orthopedic and obstetric practice, with most reports consisting of single cases.

This rare condition consists of significant osteoporosis affecting the hips and spine, causing significant morbidity, and putting young female patients at risk for vertebral and femoral neck fractures.

The pathogenesis of transient osteoporosis of pregnancy is unknown, with various theories as to its etiology.

Recently, a number of reports have described elevated levels of PTHrP in patients with transient osteoporosis in pregnancy and of the postpartum period Our goal in this study is to assess the role of PTHrP in transient osteoporosis of pregnancy


Condition
Transient Osteperosis

Study Type: Observational
Study Design: Time Perspective: Prospective

Resource links provided by NLM:


Further study details as provided by Hadassah Medical Organization:

  Eligibility

Ages Eligible for Study:   18 Years to 45 Years
Genders Eligible for Study:   Female
Criteria

Inclusion Criteria:

  • Signed Informed consent
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00541645

Sponsors and Collaborators
Hadassah Medical Organization
Investigators
Principal Investigator: Efrain Liebner, MD Hadassah Medical Organization
Study Chair: Meir Liebergall, M.D Hadassah Medical Organization
Study Director: Tzvi Bar-Shavit, Ph.D The Hebrew University
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00541645     History of Changes
Other Study ID Numbers: Lib001-HMO-CTIL
Study First Received: October 7, 2007
Last Updated: March 17, 2008
Health Authority: Israel: Ministry of Health

ClinicalTrials.gov processed this record on July 20, 2014