Bone Density in Patients With Schizophrenia
People with chronic mental disorder such as schizophrenia and alcohol abuse are high risk groups for developing osteoporosis.
To evaluate the prevalence of bone mineral density in men patients with schizophrenia with alcohol abuse, the investigators will compare bone mineral density between patient with schizophrenia with and without alcohol abuse.
|Study Design:||Observational Model: Case Control|
|Official Title:||Bone Mineral Density in the Korean Patients With Chronic Schizophrenia With Alcohol Abuse|
- The change of bone mineral density [ Time Frame: cross sectional and prospective ] [ Designated as safety issue: Yes ]
- The effects of Smoking and antipsychotic drug on BMD [ Time Frame: Cross sectional Study ] [ Designated as safety issue: Yes ]
|Study Start Date:||November 2007|
|Study Completion Date:||November 2008|
|Primary Completion Date:||November 2008 (Final data collection date for primary outcome measure)|
Chronic schizophrenia with aged 18-80 years
Other: No Intervention
People with schizophrenia has been known as a high risk groups for developing osteoporosis, because of lack of exercise, poor nutrition and high rate of smoking. Those with alcohol abuse may be higher risk group than one with schizophrenia without alcohol abuse, because they frequently have several medical problems such as liver dysfunction, Vitamin D deficiency, hyperparathyroidism and those medical condition increase risk for developing osteoporosis. Also alcohol itself can increase bone loss too by disturbing bone remodeling and enhancing bone fragility. To compare the prevalence of bone mineral density in patients with schizophrenia with alcohol abuse to those without alcohol problem, we will investigate BMD in large population of Korean patients with those illnesses.