Language in Primary Progressive Aphasia
The purpose of this study is to further define the neurological and linguistic deterioration in primary progressive aphasia.
Primary Progressive Aphasia
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Language in Primary Progressive Aphasia|
- Neuropsychological variables [ Time Frame: Immediately after testing and at two years post-testing ] [ Designated as safety issue: No ]
|Study Start Date:||May 2007|
|Estimated Study Completion Date:||April 2017|
|Estimated Primary Completion Date:||April 2017 (Final data collection date for primary outcome measure)|
Individuals with primary progressive aphasia
Individuals with no diagnosis of any type of dementia
The Language in Primary Progressive Aphasia (PPA) aims to understand the behavioral, anatomical and physiological changes in people with PPA throughout the course of the illness. The researchers in this study want to increase awareness of PPA, educate others about this unique disorder, and to encourage more research to eventually develop therapies.
During the three-day research program, participants will be asked to undergo neuropsychological testing (paper and pencil tests that evaluate cognition), an MRI (a non-invasive brain-imaging procedure), an EEG (another non-invasive procedure that looks at brain waves when you think) and other computer and language testing batteries. Participants may be asked to return every two years to complete the same measures.
The study will recruit approximately 15 participants with PPA per year. For participants not living near Chicago, IL, flights and accommodations (for both the person with PPA and their companion) will be covered by the study.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00537004
|Contact: Danielle Barkema, MSfirstname.lastname@example.org|
|United States, Illinois|
|Chicago, Illinois, United States, 60611|
|Contact: Danielle Barkema, MS 312-908-9681 email@example.com|
|Principal Investigator: M.-Marsel Mesulam, MD|
|Principal Investigator:||Marsel Mesulam, MD||Northwestern University Feinberg School of Medicine|