MicroRNA Expression and Function in Cutaneous Malignant Melanoma

This study has been completed.
Sponsor:
Information provided by:
Rigshospitalet, Denmark
ClinicalTrials.gov Identifier:
NCT00536029
First received: September 26, 2007
Last updated: NA
Last verified: September 2007
History: No changes posted
  Purpose

Spectrophotometric intracutaneous analysis (SIAscopy) is a new technique for imaging pigmented skin lesions and for diagnosing melanoma and non-melanoma skin cancer. The SIAscope is a portable system comprising of a laptop computer connected to a small handheld skin probe equipped with a light source. The skin lesion is interrogated with light of different wavelengths and the reflection spectra analysed by proprietary algorithms showing distribution, position and quantity of melanin, blood and collagen within the papillary dermis (the SIAgraphs). Earlier studies generated promising results and documented >80% specificity and sensitivity of SIAscopy for melanoma diagnosis. It has been suggested that this technique could be used for the initial screening and selection of pigmented lesion for excision. In this work we addressed the usefulness of SIAscopy for the clinical diagnosis of pigmented malignant melanoma in a prospective, blinded design.


Condition
Melanoma

Study Type: Observational
Study Design: Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
Official Title: MicroRNA Expression and Function in Cutaneous Malignant Melanoma

Resource links provided by NLM:


Further study details as provided by Rigshospitalet, Denmark:

Enrollment: 68
Study Start Date: February 2007
Study Completion Date: June 2007
Groups/Cohorts
Case: A
Subject with pigmented skin lesion suspect for malignant melanoma

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Pigmented lesion

Exclusion Criteria:

  • No pigmented lesion
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00536029

Locations
Denmark
Rigshospitalet
Copenhagen, Denmark, 2200
Sponsors and Collaborators
Rigshospitalet, Denmark
Investigators
Principal Investigator: Martin Glud, Cand.med. Department for Plastic Surgery and Burn Unit
  More Information

Publications:
ClinicalTrials.gov Identifier: NCT00536029     History of Changes
Other Study ID Numbers: H-C-2007-0009
Study First Received: September 26, 2007
Last Updated: September 26, 2007
Health Authority: Denmark: National Board of Health

Keywords provided by Rigshospitalet, Denmark:
Melanoma
SIAscope
pigmented skin lesions

Additional relevant MeSH terms:
Melanoma
Neuroendocrine Tumors
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms
Neoplasms, Nerve Tissue
Nevi and Melanomas

ClinicalTrials.gov processed this record on September 18, 2014