Preoperative Hepatic Arterial Infusion Chemotherapy
Recruitment status was Active, not recruiting
To assess the feasibility and results of liver resection after preoperative hepatic artery infusion (HAI) chemotherapy with FUDR.
|Study Design:||Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Retrospective
|Official Title:||Preoperative Hepatic Arterial Infusion Chemotherapy in Patients Undergoing Liver Resection for Colorectal Liver Metastases|
|Study Start Date:||December 1995|
Between 1995 and 2004, 239 patients with isolated colorectal liver metastases received HAI chemotherapy with neoadjuvant intent. Fifty of these patients underwent subsequent curative liver resection (HAI group).
Postoperative morbidity, liver function tests, and long term outcomes were evaluated. Adverse events related to HAI chemotherapy were also evaluated.
|Department of Surgery - Liver Unit, Scientific Institute San Raffaele,|
|Milan, Italy, 20132|
|Principal Investigator:||Luca Aldrighetti, M.D, PhD||Department of Surgery - Liver Unit, Scientific Institute San Raffaele,|