• The investigator and subject will assess the keloid sites for Global appearance, Color, Matte/Shiny, Contour, Distortion, Texture, Oozing, Redness, Warmth, Firmness. [ Time Frame: 12 (+/-2) days after excision of keloid ] [ Designated as safety issue: Yes ]
  

• The investigator and subject will assess the keloid sites for Global appearance, Color, Matte/Shiny, Contour, Distortion, Texture, Oozing, Redness, Warmth, Firmness. [ Time Frame: 3 months (+/-3 weeks) ] [ Designated as safety issue: Yes ]
  
• The investigator and subject will assess the keloid sites for Global appearance, Color, Matte/Shiny, Contour, Distortion, Texture, Oozing, Redness, Warmth, Firmness. [ Time Frame: 6 months (+/-4 weeks) ] [ Designated as safety issue: Yes ]
  

This study will be undertaken to compare the efficacy of two closure techniques for excised keloids. (1) Clozex, a non-latex, hypoallergenic adhesive polymeric interlaced film designed to adhere to proximal wound edges for 7-10 days, will be used after the punch biopsy or excision of a keloid and (2) sutures to close a similar second keloid after the punch biopsy or excision of a keloid.

On day 12, the investigator and subject will assess the keloid site(s) with the use of a visual analog scale.

There is an optional follow-up at 3 months and 6 months to assess the recurrence of the keloid and the effectiveness of the treatments with a visual analog scale.

The subject will assess the keloid site(s) with the use of the following visual analog scale:

1. Cosmetic appearance
2. Pain
3. Tenderness
4. Itching
5. Oozing
6. Redness
7. Warmth

The investigator will assess the keloid site(s) with the use of this visual analog scale:

1. Global appearance
2. Color
3. Matte/Shiny
4. Contour
5. Distortion
6. Texture
7. Oozing
8. Redness
9. Warmth
10. Firmness

Inclusion Criteria:

• Male or females, in good health, and at least 12 years of age.
• Individuals with 2 or more keloids on the trunk, arm, leg, and neck between 0.5 and 2 cm in length.
• Individuals who are willing and able to participate in the requirements of the study, including signing the informed consent.
• In the opinion of the investigator, the 2 keloids can be excised in a similar manner and closed properly with the two techniques and will benefit from the procedure.
• In the opinion of the investigator, the keloid could benefit from surgical procedure.

Exclusion Criteria:

• Individuals with keloids that do not fit into the criteria.
• Individuals who are planning pregnancy, pregnant, or breast feeding.
• Individuals with a history of medical or dermatologic conditions which, in the opinion of the investigator, would put the subject at heightened risk or would limit complicate the study evaluations required by the protocol.
• Individuals who present with excessive body hair in the designed keloid area.
• Individuals with uncontrolled diabetes.
• Individuals with autoimmune disorders (HIV/AIDs, SLE).
• Subjects who have received keloid treatment within one month of the first day of the study.
• Individuals who plan to receive keloid treatment(s) during the study.
• Individuals who are currently taking prescription or over the counter medication or interventions on a regular basis that as part of their mechanism of action, have the potential to mask an inflammatory reaction. Examples of such medications include, but are not limited to, corticosteroids, non-steroid anti-inflammatory drugs (NSAIDs), antihistamines, aspirin (81mg or less daily dosage permissible), or other medications that in the opinion of the investigator or designee may expose the subject to heightened risk or complicate the study assessments.