Estrogen and Gender Biased Autoimmunity
Recruitment status was Recruiting
This study involves research to investigate how estrogen affects women of childbearing age and its correlation to Systemic Lupus Erythematosus. The findings from this study might help determine how body cells, called T Cells, react to estrogen. The study will seek to determine if cells from women with Lupus, react differently from cells in persons without Lupus. We will attempt to identify genetic factors that determine the effects of estrogen on Lupus cells.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Estrogen and Gender Biased Autoimmunity in Systemic Lupus Erythematosus|
|Study Start Date:||April 2005|
|Estimated Study Completion Date:||December 2013|
|Estimated Primary Completion Date:||December 2013 (Final data collection date for primary outcome measure)|
Female Lupus patients
Females who are still childbearing age, not on hormones, with Systemic Lupus Erythematosus, still cycling.
Other: Peripheral lab draws
100ml blood for analysis, taken no more than 4 times in one year.
This is a 3-year study. The total number of subjects enrolled will depend on the results obtained. The subjects will be at least 18 years of age and pre-menopausal. Exclusion to include pregnant women, and all subjects are told not to get pregnant while on study. Also, they cannot take hormones by mouth or patch while on study. The study can include healthy subjects as well. Blood will be drawn (120 ml) four times a year, randomly.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00519454
|Contact: Nabih I Abdou, MD, PhD.||firstname.lastname@example.org|
|Contact: Cindy Greenwell, RNemail@example.com|
|United States, Missouri|
|The Center for Rheumatic Disease, Allergy and Immunology||Recruiting|
|Kansas City, Missouri, United States, 64111|
|Contact: Nabih I Abdou, MD, PhD 816-531-0930 firstname.lastname@example.org|
|Contact: Cindy A Greenwell, RN 816-531-0930 email@example.com|
|Principal Investigator: Nabih I Abdou, MD, PhD|
|Principal Investigator:||Nabih I Abdou, MD, PhD||The Center for Rheumatic Disease, Allergy and Immunology|