Does Sunbed Radiation With Mainly UVA Provoke Cutaneous Vitamin D Synthesis in Humans?

This study has been completed.
Sponsor:
Collaborator:
Hvidovre University Hospital
Information provided by:
Bispebjerg Hospital
ClinicalTrials.gov Identifier:
NCT00516867
First received: August 14, 2007
Last updated: August 15, 2007
Last verified: August 2007
  Purpose

We would investigate in a controlled, randomized open study in the winter season: 1) If serum levels of vitamin D (25(OH)D) increase in subjects treated with sunbed with sunlamps emitting mainly UVA and only 0·5% or 1·4% UVB compared to non-sunbed treated controls 2) If yes, are the 25(OH)D serum levels then dependent on the UVB dose?


Condition Intervention
Healthy
Radiation: UV radiation

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Pharmacokinetics Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Basic Science
Official Title: Sunbed Radiation Provoke Cutaneous Vitamin D Synthesis in Humans, a Randomized Controlled Trial

Resource links provided by NLM:


Further study details as provided by Bispebjerg Hospital:

Primary Outcome Measures:
  • Serum concentration of 25(OH)D [ Time Frame: 18 Days ]

Secondary Outcome Measures:
  • Serum concentration of PTH [ Time Frame: 18 Days ]

Enrollment: 41
Study Start Date: February 2006
Study Completion Date: April 2006
Arms Assigned Interventions
Active Comparator: UVB 0.5% Radiation: UV radiation
UV radiation with 99.5% UVA and 0.5%UVB
No Intervention: Controls
Active Comparator: UVB 1.4% Radiation: UV radiation
UVB 1.4 % and UVA 98.6

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Healthy
  • Females
  • Above 50 years
  • Younger with serum concentration of 25(OH)D below 50nmol/l

Exclusion Criteria:

  • No sunbed use last ½ year
  • No sun holiday last ½ year
  • No intake of vitamin D above 10 microgram/day
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00516867

Locations
Denmark
Bispebjerg Hospital
Copenhagen, Denmark, DK-2000 NV
Sponsors and Collaborators
Bispebjerg Hospital
Hvidovre University Hospital
Investigators
Study Chair: Hans C Wulf, MD, DSc Bispebjerg Hospital
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00516867     History of Changes
Other Study ID Numbers: KF 01 290815
Study First Received: August 14, 2007
Last Updated: August 15, 2007
Health Authority: Denmark: National Board of Health

ClinicalTrials.gov processed this record on October 19, 2014