Explanted Lung Tissues With Pulmonary Fibrosis
The goal of this study is to use the tissues from the explanted lungs in order to better study the cause of pulmonary fibrosis at a cellular level.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Utilization of Explanted Lungs for Isolation of Tissue Samples and Primary Cell Lines to Study Pulmonary Fibrosis|
- assess fibroblasts and cytokines associated with pulmonary fibrosis [ Time Frame: 12/2013 ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
explanted lung tissue
|Study Start Date:||February 2006|
|Estimated Study Completion Date:||December 2013|
|Estimated Primary Completion Date:||December 2013 (Final data collection date for primary outcome measure)|
Pulmonary Fibrosis involves scarring of the lung. Gradually, the air sacs of the lungs become replaced by fibrotic tissue. The most current thinking is that the fibrotic process is a reaction to tiny injury to the lung. When the scar forms, the tissue becomes thicker causing a permanent loss of the tissue's ability to carry oxygen into the bloodstream.
We need to obtain lung tissue from patients without pulmonary fibrosis and compare it to lung tissue from patients with pulmonary fibrosis.
|Contact: Lourdes Norwick, BSN, RNemail@example.com|
|United States, Illinois|
|The University of Chicago||Recruiting|
|Chicago, Illinois, United States, 60637|
|Contact: Laura Krupa 773-834-8903 firstname.lastname@example.org|
|Principal Investigator: Sangeeta Bhorade, MD|
|Sub-Investigator: Nathan Sandbo, MD|
|Principal Investigator:||Sangeeta Bhorade, MD||University of Chicago|