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Non-prescription Versus Prescription Topical Treatments Versus no Treatment in the Control of Sweating

This study has been completed.
Sponsor:
Information provided by:
Northwestern University
ClinicalTrials.gov Identifier:
NCT00509886
First received: July 31, 2007
Last updated: November 7, 2014
Last verified: November 2014
  Purpose

The purpose of this study is to assess the effectiveness of the prescription treatment compared to the non-prescription treatment. It is hypothesized that the prescription treatment will have a significantly greater effect than the non-prescription treatment on decreasing excess sweating.


Condition Intervention
Hyperhidrosis
Excess Sweating
Drug: Drysol
Drug: Drioff

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Prevention
Official Title: Non-prescription Versus Prescription Topical Treatments Versus no Treatment in the Control of Sweating

Resource links provided by NLM:


Further study details as provided by Northwestern University:

Primary Outcome Measures:
  • Gravimetric analysis [ Time Frame: 3 hours ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Subject sweat assessment [ Time Frame: 3 hours ] [ Designated as safety issue: No ]
  • HDSS [ Time Frame: 3 hours ] [ Designated as safety issue: No ]

Enrollment: 24
Study Start Date: June 2007
Study Completion Date: August 2007
Primary Completion Date: August 2007 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
ARMs were randomized. One side of the body received treatment with one antiperspirant and the contralateral side with a different antiperspirant.
Drug: Drysol
20% aluminum chloride hexahydrate
Experimental: 2
ARMs were randomized. One side of the body received treatment with one antiperspirant and the contralateral side with a different antiperspirant.
Drug: Drioff
1% aluminum acetate

Detailed Description:

The objective of this study is to assess the effectiveness of the prescription treatment compared to the non-prescription treatment. It is hypothesized that the prescription treatment will have a significantly greater effect than the non-prescription treatment on decreasing excess sweating.

  Eligibility

Ages Eligible for Study:   21 Years to 30 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • age 21-30 years
  • males and females
  • The subjects are in good health.
  • The subjects have willingness and the ability to understand and provide informed consent for participation in the study.

Exclusion Criteria:

  • Subjects with primary hyperhidrosis
  • Subjects who are unable to withstand prolonged heat exposure or who have self-reported history of cardiovascular or respiratory disorders.
  • Subjects who are unable to give informed consent.
  • Subjects with mental illness.
  • Subjects who are pregnant or nursing.
  • Subjects with systemic or local skin disease and/or infection that may interfere with the conduct of the study.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00509886

Locations
United States, Illinois
Northwestern University Dermatology
Chicago, Illinois, United States, 60611
Sponsors and Collaborators
Northwestern University
Investigators
Principal Investigator: Murad Alam, MD Northwestern University dermatology
Study Director: Dennis West, PhD Northwestern University dermatology
  More Information

No publications provided

Responsible Party: Murad Alam, MD, Northwestern University Dermatology department
ClinicalTrials.gov Identifier: NCT00509886     History of Changes
Other Study ID Numbers: STU00000722
Study First Received: July 31, 2007
Last Updated: November 7, 2014
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Hyperhidrosis
Skin Diseases
Sweat Gland Diseases

ClinicalTrials.gov processed this record on November 24, 2014