Complex Problem Solving Training in Schizophrenic Patients - Tabular View

Tracking Information

First Received Date ^ICMJE

July 25, 2007

Last Updated Date

May 14, 2009

Start Date ^ICMJE

August 2007

Primary Completion Date

February 2009 (final data collection date for primary outcome measure)

Current Primary Outcome Measures ^ICMJE

Functional Capacity as assessed by Osnabrücker Arbeitsfähigkeitsprofil "learning ability" subscale [ Time Frame: 3 weeks ] [ Designated as safety issue: No ]

Original Primary Outcome Measures ^ICMJE

Functional Capacity as assessed by Osnabrücker Arbeitsfähigkeitsprofil "learning ability" subscale [ Time Frame: 3 weeks ]

Change History

Complete list of historical versions of study NCT00507988 on ClinicalTrials.gov Archive Site

Current Secondary Outcome Measures ^ICMJE

Functional Capacity as assessed by the Osnabrücker-Arbeitsfähigkeitsprofil summary score [ Time Frame: 3 weeks ] [ Designated as safety issue: No ]
BADS Zoo Map Score (Neuropsychological Test) [ Time Frame: 3 weeks ] [ Designated as safety issue: No ]
Planungstest (Tower of London) Summary Score (Neuropsychological Test) [ Time Frame: 3 weeks ] [ Designated as safety issue: No ]
Plan-A-Day S Solution Time (Neuropsychological Test) [ Time Frame: 3 weeks ] [ Designated as safety issue: No ]

Original Secondary Outcome Measures ^ICMJE

Functional Capacity as assessed by the Osnabrücker-Arbeitsfähigkeitsprofil summary score [ Time Frame: 3 weeks ]
BADS Zoo Map Score (Neuropsychological Test) [ Time Frame: 3 weeks ]
Planungstest (Tower of London) Summary Score (Neuropsychological Test) [ Time Frame: 3 weeks ]
Plan-A-Day S Solution Time (Neuropsychological Test) [ Time Frame: 3 weeks ]

Descriptive Information

Brief Title ^ICMJE

Complex Problem Solving Training in Schizophrenic Patients

Official Title ^ICMJE

Complex Problem Solving Training in Schizophrenic Patients

Brief Summary

The primary purpose of the study is to assess whether a planning and problem-solving training is more effective in improving work therapy performance in patients with schizophrenia than traditional training programs addressing basic cognitive functions.

Detailed Description

In patients with schizophrenia, cognitive deficits often lead to an impairment in daily life. This observation has led to the development of cognitive training packages aiming a improving these deficits. However, it is far from clear which level of cognitive functioning provides the best target for cognitive interventions. Traditionally, training has aimed a basic cognitive functions like attention and memory. In the present study we aim at a higher-level of function, namely planning and problem-solving skills, which are trained using the software package Plan-A-Day. The primary hypothesis is that complex problem solving training improved functional capacity more than traditional training programs addressing basic cognitive function.

Study Phase

Study Type ^ICMJE

Interventional

Study Design ^ICMJE

Treatment, Randomized, Single Blind (Outcomes Assessor), Active Control, Parallel Assignment, Efficacy Study

Condition ^ICMJE

Schizophrenia
Schizoaffective Disorder

Intervention ^ICMJE

Behavioral: Complex Problem Solving Training
Behavioral: Basic Cognitive Training

Study Arms / Comparison Groups

Experimental: Complex Problem Solving Training
Active Comparator: Basic Cognitive Training

Publications *

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status ^ICMJE

Completed

Enrollment ^ICMJE

Completion Date

February 2009

Primary Completion Date

February 2009 (final data collection date for primary outcome measure)

Eligibility Criteria ^ICMJE

Inclusion Criteria:

Patients with schizophrenic or schizoaffective Disorder (DSM IV)
Remitted positive symptoms (PANSS positive all ≤ 4), clinical stability
Native German speaker
Verbal IQ > 80
Visual acuity normal or corrected to normal

Exclusion Criteria:

Concurrent Axis-I disorder
Drug abuse during last 2 months
Neurological or medical conditions potentially affecting cognition

Gender

Both

Ages

18 Years to 45 Years

Accepts Healthy Volunteers

Contacts ^ICMJE

Contact information is only displayed when the study is recruiting subjects

Location Countries ^ICMJE

Germany

Administrative Information

NCT ID ^ICMJE

NCT00507988

Responsible Party

Irmtraut Gürkan, University Hospital Heidelberg

Study ID Numbers ^ICMJE

01GW0630

Study Sponsor ^ICMJE

University of Heidelberg

Collaborators ^ICMJE

German Federal Ministry of Education and Research

Investigators ^ICMJE

Principal Investigator:

Matthias Weisbrod, MD

SRH Klinikum Karlsbad-Langensteinbach, Department of Psychiatry

Information Provided By

University of Heidelberg

Verification Date

May 2009

^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP