Cardiomyopathy Tissue Bank in a Cancer Population

This study is currently recruiting participants. (see Contacts and Locations)
Verified February 2014 by M.D. Anderson Cancer Center
Sponsor:
Information provided by (Responsible Party):
M.D. Anderson Cancer Center
ClinicalTrials.gov Identifier:
NCT00500734
First received: July 12, 2007
Last updated: February 3, 2014
Last verified: February 2014
  Purpose

The goal of this laboratory research study is to collect and store blood and tissue from patients who have a diagnosis of heart disease and may be at a high risk for the development of heart failure. This blood may be used in the future to identify genes that may play a role in developing congestive heart failure (CHF) from chemotherapy or other sources.


Condition Intervention
Heart Disease
Procedure: Blood Sample

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Cardiomyopathy Tissue Bank in a Cancer Population

Resource links provided by NLM:


Further study details as provided by M.D. Anderson Cancer Center:

Primary Outcome Measures:
  • Baseline Patient Demographic Information (age, sex, race) [ Time Frame: One time visit. ] [ Designated as safety issue: No ]
  • Identification biological markers predisposing cancer patients to development of chemotherapy-induced congestive heart failure [ Time Frame: One time visit for collection of blood and tissue samples. ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

Blood and tissue collection. This blood may be studied in the future to try to find possible genetic or biochemical markers that may be the cause of CHF.


Estimated Enrollment: 1000
Study Start Date: December 2002
Estimated Primary Completion Date: December 2015 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Heart Disease Patients Procedure: Blood Sample
One time blood draw of 2 teaspoons.

Detailed Description:

You will have a one time blood draw of 2 teaspoons of blood for use in future research. This blood may be studied in the future to try to find possible genetic or biochemical markers that may be the cause of CHF. Your blood will be drawn either on an outpatient basis or during a routine visit to the hospital. If you already have a central line or an IV placed, the blood will be drawn at these sites to decrease the pain and discomfort of the blood draw. The information obtained in this study will not be put into your medical records.

This is an investigational study. All will be enrolled at M. D. Anderson.

  Eligibility

Ages Eligible for Study:   2 Months and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Patients diagnosed with heart disease and that may be at a high risk for the development of heart failure.

Criteria

Inclusion Criteria:

  • Patients who are at high risk for developing Cardiomyopathy or Congestive Heart Failure.
  • Patients two months of age and older.

Exclusion Criteria:

  • Those that are not willing to sign an informed consent.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00500734

Contacts
Contact: Jean-Bernard Durand, MD 713-792-6239

Locations
United States, Texas
UT MD Anderson Cancer Center Recruiting
Houston, Texas, United States, 77030
Principal Investigator: Jean-Bernard Durand, MD         
Sponsors and Collaborators
M.D. Anderson Cancer Center
Investigators
Principal Investigator: Jean-Bernard Durand, MD M.D. Anderson Cancer Center
  More Information

Additional Information:
No publications provided

Responsible Party: M.D. Anderson Cancer Center
ClinicalTrials.gov Identifier: NCT00500734     History of Changes
Other Study ID Numbers: ID02-359
Study First Received: July 12, 2007
Last Updated: February 3, 2014
Health Authority: United States: Institutional Review Board

Keywords provided by M.D. Anderson Cancer Center:
Cardiomyopathy
Tissue Bank
Heart Disease
Heart Failure
Congestive Heart Failure

Additional relevant MeSH terms:
Heart Diseases
Cardiomyopathies
Cardiovascular Diseases

ClinicalTrials.gov processed this record on July 24, 2014