Anisometropia Amblyopia Improved by Perceptual Learning and Patching

This study has been completed.
Sponsor:
Information provided by:
Tri-Service General Hospital
ClinicalTrials.gov Identifier:
NCT00498641
First received: July 9, 2007
Last updated: NA
Last verified: July 2007
History: No changes posted
  Purpose

To compare the effects of perceptual learning with patching on improving visual acuity and contrast sensitivity in payient with anisometropic amblyopia.


Condition Intervention Phase
Anisometropic Amblypia
Procedure: computer program and patching
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind
Primary Purpose: Treatment

Resource links provided by NLM:


Further study details as provided by Tri-Service General Hospital:

Primary Outcome Measures:
  • Corrected amblyopic logMAR visual acuity and contrast sensitivity function

Study Start Date: January 2005
Study Completion Date: January 2007
Detailed Description:

Patients with anisometropic amblyopia were randomized to patching or perceptual learning group. Corrected amblyopic logMAR visual acuity and contrast sensitivity function were measured at four-weekly intervals until visual acuity stabilized or amblyopia resolved. Improvement in visual acuity, contrast sensitivity, and the resolution of amblyopia were compared between groups.

  Eligibility

Ages Eligible for Study:   3 Years to 55 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Anisometropia without strabismus
  • An interocular acuity difference of at least 0.2 logMAR in children (3–7 years of age) or in older children and adult patients without a history of patching or atropine penalization
  • All patients wore their spectacle at least one year

Exclusion Criteria:

  • A history of prior spectacle correction
  • A history of patching or optical penalization
  • The existence of an ocular disease that could contribute to decreased visual acuity
  • Learning difficulties
  • The presence of strabismus
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00498641

Sponsors and Collaborators
Tri-Service General Hospital
Investigators
Study Director: Po Chen, MD Tri-Service General Hospital
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00498641     History of Changes
Other Study ID Numbers: 094-05-0112
Study First Received: July 9, 2007
Last Updated: July 9, 2007
Health Authority: Taiwan: Institutional Review Board

Keywords provided by Tri-Service General Hospital:
perceptual learning
occlusion therapy

ClinicalTrials.gov processed this record on July 28, 2014