Study of Low-Dose Total Skin Electron Beam Therapy in Mycosis Fungoides
The purpise of this study was to determine the effect of low-dose (4 Gy) total skin electron beam therapy as a second-line treatment of stage IB-II mycosis fungoides.
|Study Design:||Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||A Prospective, Open-Label Study on Low-Dose Total Skin Electron Beam Therapy in Mycosis Fungoides|
- Response rates
- Duration of responses
|Study Start Date:||January 2002|
|Study Completion Date:||January 2006|
Current treatment modalities are usually not curative and having treatment options suitable for the long-term control therefore essential. Electron beam therapy is generally applied to the skin in total doses of 30-36 Gy over a 8-10 week period.Due to the potential risk of toxicity including bone marrow supression, no more than 2-3 courses in a life time are generally recommended. In the current study we explored the possibility of using lower radiation doses for total skin electron beam therapy for long-term disease control.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00496743
|Principal Investigator:||Robert Gniadecki, MD||Bispebjerg Hospital|