Protocol Memory Deficit in Patients With Obstructive Sleep Apnea Syndrome
Recruitment status was Not yet recruiting
The main objective of this study is to evaluate the evolution of memory deficit (verbal episodic memory, procedural memory, working memory, short-term memory) in Sleep Apnea Obstructive Syndrome (SAOS) patients after treatment by Continuous Positive Airway Pressure treatment (CPAP). For thus, we will compare memory tests in two separate groups of SAOS patients with “effective ” versus “ineffective” ( or sham) CPAP, before and 6 weeks after the beginning of the treatment. Thus we will assess the evolution of memory deficit, the effectiveness of the treatment on the evolution of memory deficit before and 6 weeks after the beginning of the treatment by “effective ” versus “ineffective” CPAP.
We feel the results of the tests of memory will show greater memory disorders in patients with SAOS before beginning the treatment rather than six weeks afterwards. Thus we hypothesise that, after the treatment by "effective" CPAP, the patients with SAOS will have greater improvement of their memory disorders than those treated by "sham CPAP".
|Study Design:||Allocation: Random Sample
Time Perspective: Longitudinal
Time Perspective: Prospective
|Official Title:||Comparison of the Evolution of Memory Deficit in Patients With Sleep Apnea Obstructive Syndrome (SAOS) Before and After "Effective" Versus Sham Treatment by Positive Pression Continues (PPC)|
|Study Start Date:||April 2007|
|Estimated Study Completion Date:||January 2008|
We want to assess the evolution, before and 6 weeks after the beginning of the treatment, of the significant differences of the performances of the various memory tests evaluating several forms of memory (episodic memory, working memory, short-term memory and procedural memory) according to the treatment for patients with SAOS (effective versus sham).
|Contact: Jean-Louis JP PEPIN, ProfessorPhD||00330476765516||JPepin@chu-grenoble.fr|
|Laboratoire EFCR-Functional Cardio-Respiratory Exploration Laboratory|
|Grenoble, Isere, France|
|Principal Investigator:||Jean-Louis JP Pépin, ProfessorPhD||University Hospital, Grenoble|