Using Community-Based Volunteers to Reach Non-Enrolled School Aged Children Through Community-Directed Treatment of Schistosomiasis in School-Aged Children in Rural Northern Ghana

This study has been completed.
Sponsor:
Information provided by:
DBL -Institute for Health Research and Development
ClinicalTrials.gov Identifier:
NCT00463931
First received: April 19, 2007
Last updated: NA
Last verified: April 2007
History: No changes posted
  Purpose

Schistosomiasis and soil-transmitted helminhtiasis occur throughout the developing world and are most prevalent in the poorest communitites. These worms have been linked to several nutritional and intellectual deficiencies in many endemic populations worldwide. Helminth control, though crucial has been neglected for varied reasons. Currently, interests towards the control of neglected diseases including schistosomiasis and soil-transmitted helminths has been revived through many interventions including repeated chemotherapy to help improve public health outcomes and prevent long term morbidity. This will contribute to achieving several of the Millennium Development Goals at a favourable cost. A community-directed treatment of human schistosomiasis and STH in school-aged children in rural notrhern Ghana using praziquantel and albendazole is proposed. It is planned to test the hypothesis that community-based volunteers are non-inferior and more cost effective than rural school teachers at reaching school-aged children.


Condition
Schistosomiasis
Soil-Transmitted Helminthiasis

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Longitudinal
Official Title: Using Community-Based Volunteers to Reach Non-Enrolled School-Aged Children Through Community-Directed Treatment of Schistosomiasis in School-Aged Children in Rural Northern Ghana

Resource links provided by NLM:


Further study details as provided by DBL -Institute for Health Research and Development:

Estimated Enrollment: 916
Study Start Date: September 2006
Study Completion Date: January 2007
Detailed Description:

The primary objectives of the study are:

To compare coverage rate of community based volunteers and rural school teachers in the distribution of praziquantel and albendazole to scholl-aged children To determine the cost effectiveness of using community based volunteers to distribute praziquantel and albendazole to school-aged children in rural Ghana.

Study methods:

A list of all school-aged children (6-15 years) in the study area will be generated from the Navrongo Demographic Surveillance System database and registers produced and given to all school teachers and community based volunteers who will be responsible for the distribution of the antihelminithics. The school teachers and community based volunteers will provide the drugs to both enrolled and non-enrolled school-aged children. Percentage coverage of school-aged children will be the outcome measure and compated between the school teachers and the community based volunteers. Stool and urine samples will be collected from a representative sample (916) of the children for laboratory analysis before the administration of the drugs for baseline data. Sample collection and laboratory analysis will be repeated 6 and 12 months after the first round of chemotherapy.

  Eligibility

Ages Eligible for Study:   6 Years to 15 Years
Genders Eligible for Study:   Both
Criteria

Inclusion Criteria:

  • Children between 6 and 15 years of age
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00463931

Locations
Ghana
The Navrongo Health Research Centre
Navrongo, Ghana
Sponsors and Collaborators
DBL -Institute for Health Research and Development
Investigators
Principal Investigator: Francis Anto, MD Navrongo Health Research Centre, Ghana
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00463931     History of Changes
Other Study ID Numbers: SRP-GH-FA-06
Study First Received: April 19, 2007
Last Updated: April 19, 2007
Health Authority: Ghana: Ministry of Health

Keywords provided by DBL -Institute for Health Research and Development:
Schistosomiasis
Soiltransmitted helminthiasis
Community-based volunteer
School based treatment approach

Additional relevant MeSH terms:
Helminthiasis
Schistosomiasis
Parasitic Diseases
Trematode Infections

ClinicalTrials.gov processed this record on July 20, 2014