Multidrug Resistance After Trabeculectomy With Mitomycin C
We investigate whether mitomycin C treatment during previous filtration surgery induces P-glycoprotein expression.
|Study Design:||Primary Purpose: Screening
Time Perspective: Cross-Sectional
|Official Title:||Multidrug Resistance After Trabeculectomy With Mitomycin C|
Despite the adjuvant use of mitomycin C during trabeculectomy, short-term and long-term failures still occur. We investigate whether mitomycin C treatment during previous trabeculectomy induces P-glycoprotein expression. Expression of P-glycoprotein is analysed in surgically removed Tenon tissue using immunohistochemistry.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00449631
|The University Hospital of Cologne|
|Cologne, Germany, 50924|
|Principal Investigator:||Arno Hueber, MD||University of Cologne|