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| Sponsor: | University of Aarhus |
|---|---|
| Information provided by: | University of Aarhus |
| ClinicalTrials.gov Identifier: | NCT00424957 |
Purpose
The purpose of the current study is to look into the pathogenesis of a severe medical condition causing acute episodes on the central nervous system as seen in majority of patients with liver cirrhosis.
| Condition |
|---|
|
Cirrhosis Hepatic Encephalopathy |
| Study Type: | Observational |
| Study Design: | Case Control, Cross-Sectional |
| Official Title: | Brain Energy Metabolism in Patients With Acute Hepatic Encephalopathy Measured With PET |
Eligibility| Ages Eligible for Study: | 45 Years to 65 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
| Sampling Method: | Non-Probability Sample |
6 patients with liver cirrhosis with an acute episode of hepatic encephalopathy, 6 patients with liver cirrhosis without an acute episode of hepatic encephalopathy, 6 healthy subjects age and sex matched
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Denmark | |
| PET Centre, Aarhus University Hospital | |
| Aarhus, Denmark, 8000 | |
| Study Chair: | Susanne Keiding, MD | PET Centre and Medical department V, Aarhus Sygehus, Aarhus University Hospital |
More Information
| Responsible Party: | PET Center, Aarhus University Hospital ( Peter Iversen ) |
| Study ID Numbers: | 20060120 |
| Study First Received: | January 19, 2007 |
| Last Updated: | February 4, 2009 |
| ClinicalTrials.gov Identifier: | NCT00424957 History of Changes |
| Health Authority: | Denmark: Ethics Committee; Denmark: The Danish National Committee on Biomedical Research Ethics; Denmark: Danish Dataprotection Agency |
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Ammonia Astrocytes Citric acid cycle Alpha ketoglutarate dehydrogenase |
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Liver Diseases Neurotoxicity Syndromes Fibrosis Brain Damage, Chronic Disorders of Environmental Origin Central Nervous System Viral Diseases Brain Diseases Signs and Symptoms Pathologic Processes Mental Disorders Neurobehavioral Manifestations Hepatic Insufficiency Delirium Liver Failure |
Metabolic Diseases Nervous System Diseases Poisoning Central Nervous System Diseases Confusion Encephalitis Virus Diseases Hepatic Encephalopathy Digestive System Diseases Delirium, Dementia, Amnestic, Cognitive Disorders Central Nervous System Infections Neurologic Manifestations Brain Diseases, Metabolic |