First Experimental Study of Transference-Interpretations (FEST)

This study has been completed.
Sponsor:
Collaborator:
The Research Council of Norway
Information provided by:
University of Oslo
ClinicalTrials.gov Identifier:
NCT00423462
First received: January 16, 2007
Last updated: August 24, 2007
Last verified: August 2007
  Purpose

Analysis of the ongoing patient-therapist interaction, the transference, is considered a key active ingredient in psychoanalytically oriented psychotherapy and psychoanalysis.However, one century after Sigmund Freuds's famous "Dora" case, the first clinical description of transference, no study of transference interpretations have been published.In the present study 100 out-patients were randomized to receive one year weekly dynamic psychotherapy, with and without transference interpretations. That is, one treatment component,transference interpretations, were added to a comparison condition, therapy of the same format, by the same therapists, but without use of transference interpretation.

All treatment session were audiotaped, and treatment integrity have been carefully checked. Patients were evaluated at treatment termination, one year after treatment termination and three years after treatment termination. Enrollment of patients started january 1993, and all follow-up evaluations completed by December 2005.


Condition Intervention Phase
Mood Disorders
Anxiety Disorders
Personality Disorders
Behavioral: Brief dynamic psychotherapy
Phase 2
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind
Primary Purpose: Treatment
Official Title: First Experimental Study of Transference Interpretations (FEST)

Resource links provided by NLM:


Further study details as provided by University of Oslo:

Primary Outcome Measures:
  • The Psychodynamic Functioning Scales (PFS), clinician rated
  • Inventory if Interpersonal Problems-Circumplex version (IIP-C), self-report

Secondary Outcome Measures:
  • The Global Assessment of Functioning Scale (GAF)
  • Global Severity Index (GSI) from SCL-90-R

Estimated Enrollment: 100
Study Start Date: January 1993
Estimated Study Completion Date: December 2005
Detailed Description:

This study is designed to measure specific long-term effects of transference interpretations in dynamic psychotherapy, using an experimental dismantling design. One hundred psychiatric out-patients, referred to seven study therapists, to receive exploratory dynamic psychotherapy, were randomized to one year weekly dynamic psychotherapy, with and without transference interpretations.They suffered from mood,anxiety,and personality disorders or interpersonal problems not due to a mental disorder. All treatment sessions were audiotaped and treatment integrity carefully checked.All patients have been evaluated before treatment, after treatment, one year after termination of treatment, and three years after termination of treatment. The main outcome measures were the Psychodynamic Functioning Scales (PFS) and Inventory of Interpersonal Problems-Circumplex version (IIP-C).Chang over time is assessed using linear mixed model analyses.

The main hypothesis is that patients treated with transference interpretations will have a more favourable course over the whole study period of four years.

The second hypothesis is that suitable patients, that is patients with a life long pattern of more mature object relations (QOR) and/or patients without comorbid personality disorders will do better with transference interpretations.

Insight and identification with the therapist will be analyzed as putative mediators of long-term change in interpersonal functioning

  Eligibility

Ages Eligible for Study:   20 Years to 60 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Age 20 - 60 years
  • Diagnoses Mood-disorder, non-psychotic
  • Anxiety disorders
  • Personality disorders
  • Interpersonal problems not due to a mental disorder

Exclusion Criteria:

  • Psychotic disorders
  • Bipolar disorder
  • Organic brain disorder
  • Substance abuse
  • Long-term (years) disability
  • Mental retardation
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00423462

Locations
Norway
Department of Psychiatry, Faculty of Medicine, University of Oslo
Oslo, Norway, 0881 Oslo
Sponsors and Collaborators
University of Oslo
The Research Council of Norway
Investigators
Principal Investigator: Per Høglend, M.D. Ph. D. Department of Psychiatry, Faculty of Medicine, Unoversity of Oslo
  More Information

Publications:
Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00423462     History of Changes
Other Study ID Numbers: FEST307/95
Study First Received: January 16, 2007
Last Updated: August 24, 2007
Health Authority: Norway:National Committee for Medical and Health Research Ethics

Keywords provided by University of Oslo:
Psychotherapy
Long-term effects

Additional relevant MeSH terms:
Anxiety Disorders
Personality Disorders
Mood Disorders
Mental Disorders

ClinicalTrials.gov processed this record on August 20, 2014