Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas

The recruitment status of this study is unknown because the information has not been verified recently.
Verified January 2007 by Hillel Yaffe Medical Center.
Recruitment status was  Not yet recruiting
Sponsor:
Collaborator:
Technion, Israel Institute of Technology
Information provided by:
Hillel Yaffe Medical Center
ClinicalTrials.gov Identifier:
NCT00419627
First received: January 5, 2007
Last updated: NA
Last verified: January 2007
History: No changes posted
  Purpose

The purpose of this study is to evaluate the presence of proteins in solid tumors which may lead to an immune response


Condition
Colorectal Neoplasms
Stomach Neoplasms
Pancreatic Neoplasms
Breast Neoplasms
Ovarian Cancer

Study Type: Observational
Study Design: Observational Model: Natural History
Time Perspective: Longitudinal
Official Title: Proteomic Analysis of Serology and Peptides Presented on the HLA Complex of Breast, Ovarian, Colon, Rectal, Gastric and Pancreatic Adenocarcinoma.

Resource links provided by NLM:


Further study details as provided by Hillel Yaffe Medical Center:

Estimated Enrollment: 160
Study Start Date: February 2007
Detailed Description:

The main objective of the study is to evaluate which proteins are presented by the HLA complex of solid tumors. Secondary objectives include to evaluate whether an immune response specific to these proteins has actually been provoked and whether there is a similar immune response following recurrence. Real specimens will be evaluated using PCR and mass spectrometry.

  Eligibility

Genders Eligible for Study:   Both
Criteria

Inclusion Criteria:

  • Patients with adenocarcinoma of breast, colon, rectum, ovary , stomach, pancreas

Exclusion Criteria:

  • Withdrawal of consent
  • Small specimen which does not allow to retrieve tissue without interfering with pathologic evaluation
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00419627

Contacts
Contact: Itamar Ashkenazi, M.D. 972-4-6304761 i_ashkenazi@yahoo.com

Locations
Israel
Hillel Yaffe Medical Center Not yet recruiting
Hadera, Israel, 38100
Contact: Itamar Ashkenazi, M.D.    972-4-6304761    i_ashkenazi@yahoo.com   
Sponsors and Collaborators
Hillel Yaffe Medical Center
Technion, Israel Institute of Technology
Investigators
Principal Investigator: Itamar Ashkenazi, M.D. Hillel Yaffe Medical Center
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00419627     History of Changes
Other Study ID Numbers: ProtHYMC
Study First Received: January 5, 2007
Last Updated: January 5, 2007
Health Authority: Israel: Ethics Commission

Keywords provided by Hillel Yaffe Medical Center:
proteomics of solid tumors

Additional relevant MeSH terms:
Neoplasms
Colorectal Neoplasms
Breast Neoplasms
Ovarian Neoplasms
Pancreatic Neoplasms
Stomach Neoplasms
Intestinal Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Endocrine Gland Neoplasms
Genital Neoplasms, Female
Urogenital Neoplasms
Digestive System Diseases
Gastrointestinal Diseases
Colonic Diseases
Intestinal Diseases
Rectal Diseases
Breast Diseases
Skin Diseases
Ovarian Diseases
Adnexal Diseases
Genital Diseases, Female
Endocrine System Diseases
Gonadal Disorders
Pancreatic Diseases
Stomach Diseases

ClinicalTrials.gov processed this record on September 16, 2014