Mechanism and Prevention of Remote Organ Injury Following Ruptured Aortic Aneurysm

This study is currently recruiting participants.

Verified by University Health Network, Toronto, December 2006

First Received: December 22, 2006 Last Updated: December 26, 2006 History of Changes

Sponsor:	University Health Network, Toronto
Collaborator:	The Physicians' Services Incorporated Foundation
Information provided by:	University Health Network, Toronto
ClinicalTrials.gov Identifier:	NCT00416000

Purpose

It has been estimated that 80% of deaths from abdominal aortic aneurysms results from rupture. Endovascular Aneurysm Repair (EVAR) has been applied to RAAA (Ruptured Abdominal Aortic Aneurysm) patients with reports of improvements. Despite the use of EVAR, patients have developed complications with lung and kidney function. This study will investigate certain biochemical processes that will potentially reduce these complications. Knowledge gained from this study may also be used to further research in this field through larger studies.

Condition
Abdominal Aortic Aneurysm

Study Type:	Observational
Study Design:	Screening, Cross-Sectional, Defined Population, Retrospective/Prospective Study
Official Title:	Phase 1 Study of Complement Activation Following Ruptured Abdominal Aortic Aneurysm: Combining Human Observation With Animal Experimentation to Establish a Framework for Human Therapy

Resource links provided by NLM:

MedlinePlus related topics: Aneurysms Aortic Aneurysm

U.S. FDA Resources

Further study details as provided by University Health Network, Toronto:

Estimated Enrollment:	60
Study Start Date:	January 2006

Eligibility

Ages Eligible for Study:	30 Years to 80 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Open/Elective EVAR patients

Exclusion Criteria:

Patients who do not present with abdominal aortic aneurysms or ruptured abdominal aortic aneurysm

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00416000

Contacts

Contact: Thomas F Lindsay, MD	416 340 4800 ext 4620	Thomas.Lindsay@uhn.on.ca
Contact: William Johnson	416 581 7498

Locations

Canada, Ontario
Toronto General Hospital	Recruiting
Toronto, Ontario, Canada, M5G 2C4

Sponsors and Collaborators

University Health Network, Toronto

The Physicians' Services Incorporated Foundation

Investigators

Principal Investigator:

Thomas F Lindsay, MD

TGH, UHN

More Information

No publications provided

Study ID Numbers:	06-0671B
Study First Received:	December 22, 2006
Last Updated:	December 26, 2006
ClinicalTrials.gov Identifier:	NCT00416000 History of Changes
Health Authority:	Canada: Health Canada

Keywords provided by University Health Network, Toronto:

Open/Elective EVAR patients

Additional relevant MeSH terms:

Aortic Diseases
Aneurysm
Aortic Aneurysm, Abdominal
Aneurysm, Ruptured
Wounds and Injuries
Vascular Diseases

Disorders of Environmental Origin
Rupture
Cardiovascular Diseases
Aortic Aneurysm
Aortic Rupture

ClinicalTrials.gov processed this record on February 08, 2010