Comparison of Scheimpflug Photos of the Crystalline Lens in Patients Who Have Undergone Vitrectomy Surgery and Controls

The recruitment status of this study is unknown because the information has not been verified recently.

Verified May 2008 by Barnes Retina Institute. Recruitment status was Recruiting

First Received on November 30, 2006. Last Updated on May 6, 2008 History of Changes

Sponsor:	Barnes Retina Institute
Information provided by:	Barnes Retina Institute
ClinicalTrials.gov Identifier:	NCT00406263

Purpose

Progression of nuclear sclerotic cataract after pars plana vitrectomy has been recognized for many years The mechanism for the rapid progression of nuclear sclerotic cataract remains unclear. The objective of this trial is to evaluate and compare the level and progression of cataract advancement in controls versus eyes that have undergone 20-gauge pars plana vitrectomy and 25-gauge pars plana vitrectomy.

Condition	Intervention
Nuclear Sclerotic Cataract	Procedure: Scheimpflug crystalline lens photographs

Study Type:	Observational
Study Design:	Observational Model: Case-Only Time Perspective: Prospective
Official Title:	Comparison of Scheimpflug Photos of the Crystalline Lens in Patients Who Have Undergone Vitrectony Surgery and Controls

Resource links provided by NLM:

MedlinePlus related topics: Cataract

U.S. FDA Resources

Further study details as provided by Barnes Retina Institute:

Estimated Enrollment:	105
Study Start Date:	November 2006
Estimated Study Completion Date:	January 2009

Intervention Details:

scheimpflug photographs

Detailed Description:

Approximately 105 patients will be recruited to obtain 35 control eyes that have not had pars plana vitrectomy and 35 eyes who will have undergone 20-gauge pars plana vitrectomy and 35 eyes will have undergone 25-gauge pars plana vitrectomy. Scheimpflug crystalline lens photographs will be taken for evaluation of level and progression of cataract development.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

patients undergoing vitrectony surgery and controls

Criteria

Inclusion Criteria:

phakic eyes of patients that are scheduled to undergo pars plana vitrectomy,
controls will be phakic eyes of patients that have not undergone andy kind of intraocular surgery,
age 18 and older

Exclusion Criteria:

any eye that is pseudophakic,
has had previous vitreoretinal surgery,
has had previous intravitreal injection,
previous intraocular inflammatory condition such as uveitis,
previous irradiation,
any patient with a history of ocular malignancy,
history of infectious intraocular condition

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00406263

Locations

United States, Missouri
Barnes Retina Institute	Recruiting
St. Louis, Missouri, United States, 63110
Contact: Pamela A Light, CCRC 314-367-1278 ext 2287 bristudies@barnesretinainstitute.com
Contact: Rhonda F Weeks 314-367-1278 ext 2240 bristudies@barnesretinainstitute.com

Sponsors and Collaborators

Barnes Retina Institute

Investigators

Principal Investigator:

Nancy M Holekamp, MD

Barnes Retina Institute

More Information

No publications provided

Responsible Party:	Nancy Holekamp, M.D., Barnes Retina Institute
ClinicalTrials.gov Identifier:	NCT00406263 History of Changes
Other Study ID Numbers:	06-1016
Study First Received:	November 30, 2006
Last Updated:	May 6, 2008
Health Authority:	United States: Institutional Review Board

Keywords provided by Barnes Retina Institute:

nuclear sclerotic cataract
cataract

Additional relevant MeSH terms:

Sclerosis
Cataract
Pathologic Processes
Lens Diseases
Eye Diseases

ClinicalTrials.gov processed this record on May 22, 2012