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Acrylate Intraocular Lenses in Cataract Surgery of Uveitis Patients

This study has been completed.
Sponsor:
Information provided by:
St. Franziskus Hospital
ClinicalTrials.gov Identifier:
NCT00403832
First received: November 24, 2006
Last updated: July 26, 2010
Last verified: August 2009
  Purpose

Cataract is a common complication in uveitis patients. Cataract operations with intraocular lens implantation are difficult in these patients because of complication due to the biocompatibility of the intraocular lens. In this study, uveal and capsular biocompatibility of two widely used acrylate intraocular lenses are compared.


Condition Intervention
Uveitis
Cataract
Device: intraocular lenses: Two foldable, acrylic, sharp edged IOLs: AcrySof™ (AcrySof SA60AT, Alcon), and Akreos adapt™ (Bausch & Lomb)

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Comparison of Two Different Acrylate Intraocular Lenses in Cataract Surgery in Patients With Non-infectious Uveitis

Resource links provided by NLM:


Further study details as provided by St. Franziskus Hospital:

Primary Outcome Measures:
  • visual acuity
  • cell deposits on anterior IOL surface
  • posterior capsular opacification

Estimated Enrollment: 60
Study Start Date: August 2005
Estimated Study Completion Date: February 2007
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • non infectious uveitis
  • no active inflammation
  • significant visual disturbance related to lens opacification

Exclusion Criteria:

  • vitreous opacification
  • ocular hypertension/glaucoma
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00403832

Locations
Germany
Department of Ophthalmology at St.-Franziskus Hospital
Münster, Germany, 48145
Sponsors and Collaborators
St. Franziskus Hospital
Investigators
Principal Investigator: Arnd Heiligenhaus, Md Phd Department of Ophthalmology at St.-FranziskusHospital Münster
  More Information

Additional Information:
No publications provided by St. Franziskus Hospital

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00403832     History of Changes
Other Study ID Numbers: 05-2911
Study First Received: November 24, 2006
Last Updated: July 26, 2010
Health Authority: Germany: Ethics Commission

Additional relevant MeSH terms:
Cataract
Chorioretinitis
Uveitis
Choroid Diseases
Choroiditis
Eye Diseases
Lens Diseases
Panuveitis
Retinal Diseases
Retinitis
Uveal Diseases
Uveitis, Posterior

ClinicalTrials.gov processed this record on November 20, 2014