Is it Possible to Treat Cyanide Poisoning With HBO?

This study is currently recruiting participants.

Verified by Rigshospitalet, Denmark, November 2006

First Received: November 13, 2006 No Changes Posted

Sponsor:	Rigshospitalet, Denmark
Information provided by:	Rigshospitalet, Denmark
ClinicalTrials.gov Identifier:	NCT00399100

Purpose

People who has been in a fire accident have been shown often to be cyanide poisoned as well as poisoned with carbon monoxide(CO). According to recommendations from the Danish Health Agency people who are CO poisoned must be treated with hyperbaric oxygen (HBO). We want to see if HBO treatment can also treat cyanide poisoning.

The hypothesis is that as cyanide binds the same place in the mitochondria as CO cyanide will be detached from the mitochondria like CO and diffuse back to the blood.This way it will be easier to treat with hydroxycobalamin.

Condition	Intervention
Carbon Monoxide Poisoning From Fire Accidents	Procedure: HBO - hyperbaric oxygen treatment

Study Type:	Observational
Study Design:	Longitudinal, Defined Population, Prospective Study

Resource links provided by NLM:

MedlinePlus related topics: Carbon Monoxide Poisoning Fires Oxygen Therapy Poisoning

U.S. FDA Resources

Further study details as provided by Rigshospitalet, Denmark:

Study Start Date:	November 2006
Estimated Study Completion Date:	November 2006

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both

Criteria

Inclusion Criteria:

Going to receive HBO treatment for carbon monoxide poisoning from fire accidents

Exclusion Criteria:

Under 18 years

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00399100

Contacts

Contact: Pia Lawson-Smith, Doctor	0045 3545 9455	Lawson_Smith@dadlnet.dk
Contact: Ole Hyldegaard Larsen, Doctor	0045 3545 8859

Locations

Denmark
Lab. for hyperbar medicin, afs. 4092, Anæstesi og Operationsklinikken, HOC, Rigshospitalet	Recruiting
København Ø, Denmark, 2100

Sponsors and Collaborators

Rigshospitalet, Denmark

Investigators

Principal Investigator:

Pia Lawson-Smith, Doctor

Rigshospitalet HOC, Trykkammeret

More Information

No publications provided

Study ID Numbers:	01-277/99
Study First Received:	November 13, 2006
Last Updated:	November 13, 2006
ClinicalTrials.gov Identifier:	NCT00399100 History of Changes
Health Authority:	Denmark: The Regional Committee on Biomedical Research Ethics

Additional relevant MeSH terms:

Carbon Monoxide Poisoning
Poisoning
Disorders of Environmental Origin
Gas Poisoning

ClinicalTrials.gov processed this record on February 08, 2010