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Is it Possible to Treat Cyanide Poisoning With HBO?

This study is currently recruiting participants.
Verified by Rigshospitalet, Denmark, November 2006

Sponsored by: Rigshospitalet, Denmark
Information provided by: Rigshospitalet, Denmark
ClinicalTrials.gov Identifier: NCT00399100
  Purpose

People who has been in a fire accident have been shown often to be cyanide poisoned as well as poisoned with carbon monoxide(CO). According to recommendations from the Danish Health Agency people who are CO poisoned must be treated with hyperbaric oxygen (HBO). We want to see if HBO treatment can also treat cyanide poisoning.

The hypothesis is that as cyanide binds the same place in the mitochondria as CO cyanide will be detached from the mitochondria like CO and diffuse back to the blood.This way it will be easier to treat with hydroxycobalamin.


Condition Intervention
Carbon Monoxide Poisoning From Fire Accidents
Procedure: HBO - hyperbaric oxygen treatment

MedlinePlus related topics:   Carbon Monoxide Poisoning    Fires    Poisoning   

U.S. FDA Resources

Study Type:   Observational
Study Design:   Longitudinal, Defined Population, Prospective Study

Further study details as provided by Rigshospitalet, Denmark:

Study Start Date:   November 2006
Estimated Study Completion Date:   November 2006

  Eligibility
Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both

Criteria

Inclusion Criteria:

  • Going to receive HBO treatment for carbon monoxide poisoning from fire accidents

Exclusion Criteria:

  • Under 18 years
  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00399100

Contacts
Contact: Pia Lawson-Smith, Doctor     0045 3545 9455     Lawson_Smith@dadlnet.dk    
Contact: Ole Hyldegaard Larsen, Doctor     0045 3545 8859    

Locations
Denmark
Lab. for hyperbar medicin, afs. 4092, Anæstesi og Operationsklinikken, HOC, Rigshospitalet     Recruiting
      København Ø, Denmark, 2100

Sponsors and Collaborators
Rigshospitalet, Denmark

Investigators
Principal Investigator:     Pia Lawson-Smith, Doctor     Rigshospitalet HOC, Trykkammeret    
  More Information


Study ID Numbers:   01-277/99
First Received:   November 13, 2006
Last Updated:   November 13, 2006
ClinicalTrials.gov Identifier:   NCT00399100
Health Authority:   Denmark: The Regional Committee on Biomedical Research Ethics

Study placed in the following topic categories:
Carbon Monoxide Poisoning
Poisoning
Disorders of Environmental Origin

Additional relevant MeSH terms:
Gas Poisoning

ClinicalTrials.gov processed this record on October 10, 2008




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