Hydrogen Sulfide Production by Oral Microflora

This study has been completed.

First Received: November 6, 2006 Last Updated: February 1, 2009 History of Changes

Sponsor:	Hadassah Medical Organization
Information provided by:	Hadassah Medical Organization
ClinicalTrials.gov Identifier:	NCT00396539

Purpose

Oral malodor is a common condition. In most cases this condition results from the proteolytic activity of anaerobic oral bacteria. These bacteria produce volatile sulfide compounds which are fowl smelling and are felt during exhalation and speech. the aim of the present study is to examine a simple method of detecting these bacteria in samples taken from the oral cavity of oral malodor patients.

Condition
Oral Malodor (Halitosis)

Study Type:	Observational
Study Design:	Prospective
Official Title:	Detection of Hydrogen Sulfide Production by Oral Microflora Samples

Further study details as provided by Hadassah Medical Organization:

Estimated Enrollment:	60
Study Start Date:	January 2007
Study Completion Date:	September 2008
Primary Completion Date:	August 2008 (Final data collection date for primary outcome measure)

Eligibility

Ages Eligible for Study:	18 Years to 45 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

oral malodor patients

Exclusion Criteria:

smokers, users of antibiotic one month prior to study

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00396539

Locations

Israel
Hadassah Medical Organization
Jerusalem, Israel

Sponsors and Collaborators

Hadassah Medical Organization

Investigators

Principal Investigator:

Nir Sterer, Dr.

Hadassah Medical Organization

More Information

No publications provided

Study ID Numbers:	29.12.06-19-HMO-CTIL
Study First Received:	November 6, 2006
Last Updated:	February 1, 2009
ClinicalTrials.gov Identifier:	NCT00396539 History of Changes
Health Authority:	Israel: Israeli Health Ministry Pharmaceutical Administration

Additional relevant MeSH terms:

Signs and Symptoms
Signs and Symptoms, Digestive
Halitosis

ClinicalTrials.gov processed this record on November 27, 2009