Renal Artery Calcium and Hypertension - Full Text View

Purpose

CT of the abdomen is a very common examination performed for various indications.One of the common findings is vascular calcifications including calcifications of the renal arteries.Calcifications in the carotid arteries and coronary arteries are good predictor for obstructive atherosclerotic disease.Stenosis of the renal arteries can cause symptomatic or asymptomatic hypertension with subsequent clinical sequelae. Therefore early diagnosis of this condition is imperative.

The goal of our study is to investigate the correlation between incidental calcifications of the renal arteries in CT examinations and the presence of actual stenosis of these vessels in patients with and without hypertension.

Condition

Hypertension
Atherosclerosis

Genetics Home Reference related topics:

Vascular Diseases

MedlinePlus related topics:

High Blood Pressure

ChemIDplus related topics:

Calcium gluconate

U.S. FDA Resources

Study Type:	Observational
Study Design:	Screening, Longitudinal, Defined Population, Prospective Study

Official Title:	Calcifications of the Renal Arteries and Renal Artery Stenosis in Patients With and Without Hypertension?

Further study details as provided by Hadassah Medical Organization:

Estimated Enrollment:	300
Study Start Date:	November 2006

Detailed Description:

Every patient aged 30-100 referred for abdominal CT examination with IV contrast injection will be included in this study (total 300 patients.Prior to the examination relevant clinical data including history of hypertension and predisposing conditions for atherosclerotic disease, will be investigated. The patient will undergo conventional CT with no special procedures. The images will be review by the radiologist for the presence of renal arteries calcifications, renal arteries stenosis,plaque location, plaque burden and characterization and secondary renal pathology.

This study will not change the examination technique and is not associated with any inconvenience to the patients.

Eligibility

Ages Eligible for Study:	30 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Every patient referred fo abdominal CT aged 30-100

Exclusion Criteria:

Contraindication for IV contrast injection failure to demonstrate renal arteries with contrast refusal to sign an informed consent

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00388869

Contacts


Contact: Nurith Hiller, MD	972-50-7874980	hiller@netvision.net.il

Locations


Israel
	Hadassah Medical Organization	Not yet recruiting
	Jerusalem, Israel
	Contact: Arik Tzukert, DMD 00-972-2-6776095 arik@hadassah.org.il
	Contact: Hadas Lemberg, phD 00-972-2-6777572 lhadas@hadassah.org.il
	Principal Investigator: Nurith Hiller, MD

Sponsors and Collaborators

Hadassah Medical Organization

Investigators


Principal Investigator:	Nurith Hiller, MD	Hadassah Medical Organization, Jerusalem, Israel

More Information

Study ID Numbers:	HILLER-HMO-CTIL
First Received:	October 15, 2006
Last Updated:	October 16, 2006
ClinicalTrials.gov Identifier:	NCT00388869
Health Authority:	Israel: Israeli Health Ministry Pharmaceutical Administration