Fish Oil (Omega 3), Immune Function, and Mood - Full Text View

Purpose

This study is designed to examine the effects of fish oil on immune function and mood.

Condition	Intervention	Phase
Inflammation	Dietary Supplement: Omega 3 (Fish Oil) Supplementation	Phase II

ChemIDplus related topics:

Fish oil

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Efficacy Study

Official Title:	Omega-3 Dietary Supplementation, Immune Function, and Mood

Further study details as provided by National Institute on Aging (NIA):

Primary Outcome Measures:

immune function
mood

Estimated Enrollment:	138
Study Start Date:	September 2006
Estimated Study Completion Date:	December 2010
Estimated Primary Completion Date:	December 2010 (Final data collection date for primary outcome measure)

Detailed Description:

The beneficial effects of fish oil (or eating fish more frequently) include reductions in triglycerides, blood pressure, and heart rate, as well as increases in HDL cholesterol, the "good" type of cholesterol. In addition, certain aspects of immune function also appear to show favorable responses to fish oil supplementation, and some studies suggest that fish oil helps to improve mood and decrease depression.

This study is designed to examine how supplementation with omega-3 polyunsaturated fatty acids (key fish oil components) affects aspects of your immune response, and your mood; because some research suggests that people who eat more fish may do better during stressful times, the study will also examine how fish oil affects your immune response to stress, certain stress hormone responses, and your psychological response to stress.

For detailed information about the study, please visit our website at http://www.stressandhealth.org

Eligibility

Ages Eligible for Study:	40 Years to 80 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Recruiting men and women ages 50-80 from the Greater Columbus Ohio area. Participation involves taking capsules for 4 months and completing 7 appointments (for a total of 17 hours) at Ohio State.

Inclusion Criteria:

Healthy men and women
NOT currently taking any sort of fish oil or omega 3 supplement

Exclusion Criteria:

Use of blood pressure medicines, cholesterol-lowering drugs, steroids, or antidepressants
Certain lifestyle habits such as smoking or exercising vigorously for 2 or more hours a week may also exclude applicants from participating

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00385723

Contacts


Contact: Michael Di Gregorio	614-292-0386	stressandhealth@osu.edu

Locations


United States, Ohio
	The Ohio State University	Recruiting
	Columbus, Ohio, United States, 43210

Sponsors and Collaborators

National Institute on Aging (NIA)

Ohio State University

Investigators


Principal Investigator:	Janice K. Kiecolt-Glaser	Ohio State University

More Information

Please click here to visit our website if you would like to read more about the study or apply to participate. This link exits the ClinicalTrials.gov site

This link exits the ClinicalTrials.gov site

Study ID Numbers:	AG0087, 2006H0054, R01 AG029562
First Received:	October 10, 2006
Last Updated:	May 29, 2008
ClinicalTrials.gov Identifier:	NCT00385723
Health Authority:	United States: Federal Government

Keywords provided by National Institute on Aging (NIA):

affect

inflammation

Study placed in the following topic categories:

Inflammation

Additional relevant MeSH terms:

Pathologic Processes

ClinicalTrials.gov processed this record on July 03, 2008

Sponsors and Collaborators:	National Institute on Aging (NIA) Ohio State University
Information provided by:	National Institute on Aging (NIA)
ClinicalTrials.gov Identifier:	NCT00385723