The Combined Effect of 2,3-Dimercaptosuccinic Acid and Multi-Nutrients on Children in Lead Poisoning

This study has been completed.
Sponsor:
Information provided by:
China Medical University, China
ClinicalTrials.gov Identifier:
NCT00374894
First received: September 11, 2006
Last updated: NA
Last verified: April 2004
History: No changes posted
  Purpose

Lead poisoning remains a common disease among children despite successful public health efforts that reduced its prevalence.Our study was designed to test the hypothesis that lead-poisoning children (BLLs:100-440µg/L) who were given DMSA and multi-nutrients would have a greater fall than children of other groups at 12 weeks of follow-up.


Condition Intervention
Lead Poisoning
Drug: 2,3-dimercaptosuccinic acid

Study Type: Observational
Study Design: Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal

Resource links provided by NLM:


Further study details as provided by China Medical University, China:

Estimated Enrollment: 500
Study Start Date: March 2004
Estimated Study Completion Date: August 2004
  Eligibility

Ages Eligible for Study:   3 Years to 6 Years
Genders Eligible for Study:   Both
Criteria

Inclusion Criteria:

  • Initial BLLs 100-440µg/L
  • Age 3-6y
  • No more than two main residences
  • House cleaned (no lead contaminated)
  • Normal intake history and physical

Exclusion Criteria:

  • Chelation in the past 12 weeks
  • Concomitant Fe deficiency(ferritin<16ng/ml)
  • Hemoglobin<10.5g/dL
  • Medications affecting mineral metabolism
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00374894

Locations
China, Liaoning
China Medical University
Shenyang, Liaoning, China, 110001
Sponsors and Collaborators
China Medical University, China
Investigators
Study Director: Jin Ya ping, professor Department of Environmental and Occupational Health
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00374894     History of Changes
Other Study ID Numbers: 20032063 - 2001102049
Study First Received: September 11, 2006
Last Updated: September 11, 2006
Health Authority: China: Ministry of Health

Keywords provided by China Medical University, China:
2,3-dimercaptosuccinic acid
Blood Lead Levels
children
multi-nutrients

Additional relevant MeSH terms:
Poisoning
Lead Poisoning
Chemically-Induced Disorders

ClinicalTrials.gov processed this record on September 30, 2014